STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
about
Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growthLoss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice.Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayGrowth factors induce differential phosphorylation profiles of the Hrs-STAM complex: a common node in signalling networks with signal-specific propertiesIdentification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein.Therapeutic targeting of Janus kinasesGrf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LATJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPIdentification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathwaysSTAM2, a new member of the STAM family, binding to the Janus kinasesCytokine-independent Jak3 activation upon T cell receptor (TCR) stimulation through direct association of Jak3 and the TCR complexInvolvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomesThe ENTH domainTransforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screeningHrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkheadPyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathwayNovel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.VHS domain marks a group of proteins involved in endocytosis and vesicular trafficking.Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4Mutations in severe combined immune deficiency (SCID) due to JAK3 deficiency.VHS domain -- a longshoreman of vesicle lines.Jak2 is involved in c-Myc induction by Bcr-Abl.Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.STAM/EAST/Hbp adapter proteins--integrators of signalling pathways.The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Expression of the c-myc proto-oncogene is essential for HIV-1 infection in activated T cells.STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking.JAK2-STAT5B pathway and osteoblast differentiation.ESCRT & Co.The signaling mechanism of eosinophil activation.JAK3 pathway is constitutively active in B-lineage acute lymphoblastic leukemia.Zinc-finger protein 331, a novel putative tumor suppressor, suppresses growth and invasiveness of gastric cancer.Rapid purification of protein complexes from mammalian cellsDown-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression.
P2860
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P2860
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
STAM, signal transducing adapt ...... ell growth and c-myc induction
@ast
STAM, signal transducing adapt ...... ell growth and c-myc induction
@en
STAM, signal transducing adapt ...... ell growth and c-myc induction
@nl
type
label
STAM, signal transducing adapt ...... ell growth and c-myc induction
@ast
STAM, signal transducing adapt ...... ell growth and c-myc induction
@en
STAM, signal transducing adapt ...... ell growth and c-myc induction
@nl
prefLabel
STAM, signal transducing adapt ...... ell growth and c-myc induction
@ast
STAM, signal transducing adapt ...... ell growth and c-myc induction
@en
STAM, signal transducing adapt ...... ell growth and c-myc induction
@nl
P2093
P1433
P1476
STAM, signal transducing adapt ...... ell growth and c-myc induction
@en
P2093
K Sugamura
T Takeshita
P304
P356
10.1016/S1074-7613(00)80288-5
P407
P577
1997-04-01T00:00:00Z