Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cyclepRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4FHTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progressionNegative regulation of transcription by the type II arginine methyltransferase PRMT5A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyAnalysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repressionE2f3 is critical for normal cellular proliferationOncolytic Replication of E1b-Deleted AdenovirusesA 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinasep65 Negatively regulates transcription of the cyclin E geneMolecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin ES phase and meristem-specific expression of the tobacco RNR1b gene is mediated by an E2F element located in the 5' leader sequence.Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.Dysregulation of cyclin E gene expression in human cytomegalovirus-infected cells requires viral early gene expression and is associated with changes in the Rb-related protein p130.Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.Indole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysisG1 arrest and differentiation can occur independently of Rb family function.The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells.Api5 contributes to E2F1 control of the G1/S cell cycle phase transition.Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene.cAMP-mediated induction of cyclin E sensitizes growth-arrested adipose stem cells to DNA damage-induced apoptosis.Aberrant Promoter Methylation at CpG Cytosines Induce the Upregulation of the E2F5 Gene in Breast CancerRegulation of transcription and chromatin structure by pRB: here, there and everywhere.Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer.Accumulation of cyclin E is not a prerequisite for passage through the restriction point.c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulationRetinoblastoma protein transcriptional repression through histone deacetylation of a single nucleosome.Thyroid hormone - triiodothyronine - has contrary effect on proliferation of human proximal tubules cell line (HK2) and renal cancer cell lines (Caki-2, Caki-1) - role of E2F4, E2F5 and p107, p130.An E2F-binding site mediates the activation of the proliferative isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by phosphatidylinositol 3-kinaseThe mechanism of cell cycle regulation by v-Src.Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells.Overexpression of cyclin E in Mongolian gerbil with Helicobacter pylori-induced gastric precancerosis.Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression.Cell cycle regulation of the tobacco ribonucleotide reductase small subunit gene is mediated by E2F-like elements.A B-myb promoter corepressor site facilitates in vivo occupation of the adjacent E2F site by p107 x E2F and p130 x E2F complexes.Thyroid hormone receptor-beta (TR beta 1) impairs cell proliferation by the transcriptional inhibition of cyclins D1, E and A2.The periodic down regulation of Cyclin E gene expression from exit of mitosis to end of G(1) is controlled by a deacetylase- and E2F-associated bipartite repressor element.Functional characterization of E2F3b in human HepG2 liver cancer cell line.Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer.
P2860
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P2860
Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@ast
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@en
type
label
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@ast
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@en
prefLabel
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@ast
Timing of cyclin E gene expres ...... ment with a novel E2F complex.
@en
P2093
P2860
P356
P1433
P1476
Timing of cyclin E gene expres ...... ement with a novel E2F complex
@en
P2093
Fabbrizio E
Ng Eaton E
P2860
P304
P356
10.1093/EMBOJ/18.7.1878
P407
P577
1999-04-01T00:00:00Z