Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.
about
Opposite role of Bax and BCL-2 in the anti-tumoral responses of the immune systemBAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrestBcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activityDeletion of Bid impedes cell proliferation and hepatic carcinogenesisMajor role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retinaEssential role of BAX,BAK in B cell homeostasis and prevention of autoimmune diseasebcl-2 overexpression promotes myocyte proliferationEpithelial cell proliferation contributes to airway remodeling in severe asthma.Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancerp27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.Initiation of premature senescence by Bcl-2 in hypoxic condition.Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapyThe basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators.BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasionNFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network.Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions.The Bcl-2 family: roles in cell survival and oncogenesis.Gfer is a critical regulator of HSC proliferation.Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells.Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci.Non-apoptotic functions of apoptosis-regulatory proteins.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesRetinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit.Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells.Microarray and pathway analysis reveals decreased CDC25A and increased CDC42 associated with slow growth of BCL2 overexpressing immortalized breast cell line.Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell deathEvidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1Regulation of B-cell entry into the cell cycleProtect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival.Cell death in mammalian cell culture: molecular mechanisms and cell line engineering strategiesBiomarkers of therapeutic response to BCL2 antagonists in cancer.Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.Bcl-2 overexpression in hepatic stellate cell line CFSC-2G, induces a pro-fibrotic state.Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry.Endothelial adhesion of synchronized gastric tumor cells changes during cell cycle transit and correlates with the expression level of CD44 splice variants.BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.Tumor cell senescence response produces aggressive variants.G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.
P2860
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P2860
Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@ast
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@en
type
label
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@ast
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@en
prefLabel
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@ast
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@en
P2093
P2860
P1476
Bcl-2 retards cell cycle entry ...... 0, and altered E2F regulation.
@en
P2093
J A DeCaprio
P2860
P304
P356
10.1128/MCB.20.13.4745-4753.2000
P407
P577
2000-07-01T00:00:00Z