The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.
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Molecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels.A specific tryptophan in the I-II linker is a key determinant of beta-subunit binding and modulation in Ca(V)2.3 calcium channelsNeuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channelsSynaptic targeting of N-type calcium channels in hippocampal neuronsRegulation of voltage-gated calcium channel activity by the Rem and Rad GTPasesAminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunitA short history of voltage-gated calcium channelsLoss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac deathAlternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channelsThe importance of occupancy rather than affinity of CaV(beta) subunits for the calcium channel I-II linker in relation to calcium channel functionSelective up-regulation of NMDA-NR1 receptor expression in myenteric plexus after TNBS induced colitis in rats.The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsCa(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequencesThe Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearingModal gating of human CaV2.1 (P/Q-type) calcium channels: I. The slow and the fast gating modes and their modulation by beta subunitsDirect interaction of CaVβ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytesPain perception in mice lacking the beta3 subunit of voltage-activated calcium channelsNew short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channelGenome-wide association analysis identifies 13 new risk loci for schizophreniaEvidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channelsThe voltage-dependent calcium channel beta subunit contains two stable interacting domainsRab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channelsCacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsyDifferential regulated interactions of calcium/calmodulin-dependent protein kinase II with isoforms of voltage-gated calcium channel beta subunitsCbln1 is essential for interaction-dependent secretion of Cbln3The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient miceCompartmentalized beta subunit distribution determines characteristics and ethanol sensitivity of somatic, dendritic, and terminal large-conductance calcium-activated potassium channels in the rat central nervous systemThe ß subunit of voltage-gated Ca2+ channelsDeterminants of the voltage dependence of G protein modulation within calcium channel beta subunits.Functional modularity of the beta-subunit of voltage-gated Ca2+ channels.A CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels.Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout miceGABAA receptor membrane insertion rates are specified by their subunit composition.Dominant-negative suppression of Cav2.1 currents by alpha(1)2.1 truncations requires the conserved interaction domain for beta subunits.Transfer of beta subunit regulation from high to low voltage-gated Ca2+ channels.Facilitation versus depression in cultured hippocampal neurons determined by targeting of Ca2+ channel Cavbeta4 versus Cavbeta2 subunits to synaptic terminalsLocalization and targeting of voltage-dependent ion channels in mammalian central neurons.Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.
P2860
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P2860
The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@ast
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@en
type
label
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@ast
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@en
prefLabel
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@ast
The I-II loop of the Ca2+ chan ...... tagonized by the beta subunit.
@en
P2093
P1433
P1476
The I-II loop of the Ca2+ chan ...... ntagonized by the beta subunit
@en
P2093
P304
P356
10.1016/S0896-6273(00)80881-8
P407
P577
2000-01-01T00:00:00Z