The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
about
Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsPhysical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expressionInduction of p57(KIP2) expression by p73beta.SSRP1 functions as a co-activator of the transcriptional activator p63PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiationA new invertebrate member of the p53 gene family is developmentally expressed and responds to polychlorinated biphenyls.Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer TherapyTumor suppressor p53 and its gain-of-function mutants in cancerESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the questionMechanisms controlling differential promoter-occupancy by the yeast forkhead proteins Fkh1p and Fkh2p: implications for regulating the cell cycle and differentiation.The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic TargetThe microRNA feedback regulation of p63 in cancer progressionTwo molecularly distinct intracellular pathways to oligodendrocyte differentiation: role of a p53 family protein.The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compoundEpstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73αp63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tractSolution structure and binding specificity of the p63 DNA binding domainDystroglycan is involved in skin morphogenesis downstream of the Notch signaling pathway.Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium.Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.Differences in the transactivation domains of p53 family members: a computational study.Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascadeThe human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells.∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD).An invertebrate mdm homolog interacts with p53 and is differentially expressed together with p53 and ras in neoplastic Mytilus trossulus haemocytes.Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifsNF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiationMDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma.Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20QDown-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer propertiesSynergistic Effects of the Green Tea Extract Epigallocatechin-3-gallate and Taxane in Eradication of Malignant Human Prostate Tumors.p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.TAp73 promotes anabolismUpregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death
P2860
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P2860
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@ast
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@en
type
label
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@ast
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@en
prefLabel
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@ast
The p53/p63/p73 family of transcription factors: overlapping and distinct functions.
@en
P2093
P1476
The p53/p63/p73 family of transcription factors: overlapping and distinct functions
@en
P2093
P304
P407
P478
113 ( Pt 10)
P577
2000-05-01T00:00:00Z