Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease.
about
The role of saposin C in Gaucher diseaseHigh throughput screening for small molecule therapy for Gaucher disease using patient tissue as the source of mutant glucocerebrosidaseGenome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variationCalcium signaling via two-pore channels: local or global, that is the question.TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADPDiscovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidaseBiomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies.Biochemistry of glycosphingolipid storage disorders: implications for therapeutic interventionStereodivergent synthesis of right- and left-handed iminoxylitol heterodimers and monomers. Study of their impact on β-glucocerebrosidase activity.Glycosphingolipids--nature, function, and pharmacological modulation.Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase.The N370S (Asn370-->Ser) mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and saposin CStabilization of Glucocerebrosidase by Active Site Occupancy.Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signalingEffects of calcium on phosphatidylserine- and saposin C-stimulated glucosylceramide beta-glucosidase activityGaucher disease phenotypes outflanked?
P2860
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P2860
Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease.
description
1993 nî lūn-bûn
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1993 թուականի Մարտին հրատարակուած գիտական յօդուած
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1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
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1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@ast
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@en
type
label
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@ast
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@en
prefLabel
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@ast
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@en
P2093
P2860
P356
P1476
Role of pH in determining the ...... ase in type 1 Gaucher disease.
@en
P2093
Barranger JA
Sa Miranda MC
van Weely S
van den Berg M
P2860
P304
P356
10.1172/JCI116276
P407
P577
1993-03-01T00:00:00Z