Deoxyhypusine synthase generates and uses bound NADH in a transient hydride transfer mechanism.
about
Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralogReversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthaseMolecular evolution by change of function. Alkaloid-specific homospermidine synthase retained all properties of deoxyhypusine synthase except binding the eIF5A precursor proteinA new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complexStructure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NADInhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetesIdentification and characterization of a novel deoxyhypusine synthase in Leishmania donovani.Cryptosporidium parvum has an active hypusine biosynthesis pathway.Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensorStall no more at polyproline stretches with the translation elongation factors EF-P and IF-5A.A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.NADH binds and stabilizes the 26S proteasomes independent of ATP.Human deoxyhypusine synthase: interrelationship between binding of NAD and substrates.
P2860
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P2860
Deoxyhypusine synthase generates and uses bound NADH in a transient hydride transfer mechanism.
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@ast
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@en
type
label
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@ast
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@en
prefLabel
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@ast
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@en
P2093
P2860
P356
P1476
Deoxyhypusine synthase generat ...... nt hydride transfer mechanism.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.13.9170
P407
P577
2000-03-01T00:00:00Z