Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer.
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Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicumGriseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastineHigh-Throughput Excipient Discovery Enables Oral Delivery of Poorly Soluble PharmaceuticalsLive visualizations of single isolated tubulin protein self-assembly via tunneling current: effect of electromagnetic pumping during spontaneous growth of microtubule.Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organismsCytotoxicity of three South African medicinal plants using the Chang liver cell line.Effects of griseofulvin on apoptosis through caspase-3- and caspase-9-dependent pathways in K562 leukemia cells: An in vitro study.Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity.Regiodivergent addition of phenols to allylic oxidesGenome sequencing and secondary metabolism of the postharvest pathogen Penicillium griseofulvumInfluence of Alternative Tubulin Inhibitors on the Potency of a Epirubicin-Immunochemotherapeutic Synthesized with an Ultra Violet Light-Activated Intermediate: Influence of incorporating an internal/integral disulfide bond structure and AlternativeC1, a highly potent novel curcumin derivative, binds to tubulin, disrupts microtubule network and induces apoptosis.A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.Microtubules as antifungal and antiparasitic drug targets.Centrosome clustering and chromosomal (in)stability: a matter of life and death.Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy.Anticancer and antifungal compounds from Aspergillus, Penicillium and other filamentous fungi.Oxidative Cyclization in Natural Product BiosynthesisThe anti-mitotic drug griseofulvin induces apoptosis of human germ cell tumor cells through a connexin 43-dependent molecular mechanism.Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin.Anti-Neoplastic Cytotoxicity of Gemcitabine-(C4-amide)-[anti-HER2/neu] in Combination with Griseofulvin against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3).Antiproliferative Activity of Crocin Involves Targeting of Microtubules in Breast Cancer CellsComplexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin.Chemosensitization as a means to augment commercial antifungal agents.Design, Synthesis, and Cytotoxicity Evaluation of Novel Griseofulvin Analogues with Improved Water Solubility.Exploring the binding sites and binding mechanism for hydrotrope encapsulated griseofulvin drug on γ-tubulin protein.Effects of griseofulvin on in vitro porcine oocyte maturation and embryo development.Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles.
P2860
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P2860
Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Kinetic suppression of microtu ...... se in the treatment of cancer.
@ast
Kinetic suppression of microtu ...... se in the treatment of cancer.
@en
type
label
Kinetic suppression of microtu ...... se in the treatment of cancer.
@ast
Kinetic suppression of microtu ...... se in the treatment of cancer.
@en
prefLabel
Kinetic suppression of microtu ...... se in the treatment of cancer.
@ast
Kinetic suppression of microtu ...... se in the treatment of cancer.
@en
P2093
P2860
P356
P1476
Kinetic suppression of microtu ...... se in the treatment of cancer.
@en
P2093
Dulal Panda
K Rathinasamy
Leslie Wilson
Manas K Santra
P2860
P304
P356
10.1073/PNAS.0501821102
P407
P577
2005-06-28T00:00:00Z