Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6

Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6

Item

http://www.wikidata.org/entity/Q33896527

Q33896527

about

Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis Role of S3 and S4 transmembrane domain charged amino acids in channel biogenesis and gating of KCa2.3 and KCa3.1 Positive charges of translocating polypeptide chain retrieve an upstream marginal hydrophobic segment from the endoplasmic reticulum lumen to the translocon.Emerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.Defining the BK channel domains required for beta1-subunit modulation.Voltage sensor mutations differentially target misfolded K+ channel subunits to proteasomal and non-proteasomal disposal pathways.A cyclic nucleotide-gated channel mutation associated with canine daylight blindness provides insight into a role for the S2 segment tri-Asp motif in channel biogenesis.Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly.A cell-free translocation system using extracts of cultured insect cells to yield functional membrane proteins.Marginally hydrophobic transmembrane α-helices shaping membrane protein folding.Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain.The Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding.S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel Conduits of life's spark: a perspective on ion channel research since the birth of neuron.Transmembrane segments form tertiary hairpins in the folding vestibule of the ribosome.Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains.Refined topology model of the STT3/Stt3 protein subunit of the oligosaccharyltransferase complex.Contributions of counter-charge in a potassium channel voltage-sensor domain.Requirement of negative residues, Asp 95 and Asp 105, in S2 on membrane integration of a voltage-dependent K+ channel, KAT1.Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction.Heteromeric K+ channels in plants.Topogenic properties of transmembrane segments of Arabidopsis thaliana NHX1 reveal a common topology model of the Na+/H+ exchanger family.Molecular dissection of the contribution of negatively and positively charged residues in S2, S3, and S4 to the final membrane topology of the voltage sensor in the K+ channel, KAT1.Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.

P2860

Q24645170-A2FC2D47-D32A-4BFD-921C-16750B78E3C0 Q24652943-4EA4492F-F839-4C84-8126-BBC7A41F7E5D Q33907071-F9ACB792-9776-4452-BFEF-63A2DADF1A41 Q34066888-FBE243B4-FB79-4F9F-8BB7-5DF6AF85B2A3 Q34287940-3C815296-4167-4CBA-9264-542A5F1045C4 Q34596930-29911C3F-7789-4BD4-BF2B-AE00D33B5EF6 Q35006046-BB398820-FA89-455D-9231-490F96B0FEDA Q35106274-E7E8B77F-69D5-4A30-8413-961E92657A56 Q35191191-BD693732-02FA-40CC-872C-560770FB8CFA Q35500492-C8A5BB64-35F9-4A21-8A6A-97AA0164B1CA Q35846068-4436B9E4-8F26-4F23-A75B-2B31DCC0267B Q35854813-648D4E1F-B31B-48AA-8D46-8B216C7274EE Q36323490-C6055B29-8A87-44D2-A552-54A687983079 Q37338024-0DB22D48-DB42-4CF7-9284-2AF7DCDE3E19 Q37401733-673C6705-C27E-4534-82BF-52468CCAD044 Q37412726-7333C58B-175D-407F-910E-794B7021024A Q37729614-9F7592EF-9125-4D94-B148-33D50BBA874C Q38682991-27085890-1734-437B-AA9A-CB9F24E77F43 Q42023842-08AB9C34-265A-4BB5-A57C-BEC293F9BA88 Q44464467-F446758B-AFDE-42C5-A889-11D72C7D6F7E Q44683530-9CEB0883-95C6-4585-9442-110A0EFDEB77 Q46697269-B2117FE0-D2DC-4320-8B3B-808BC0B640F8 Q46792250-4C70B0D0-3245-434B-B697-0D0B40200F84 Q48836558-A1F531DA-E461-4450-82F2-521469E93F13 Q55385752-3F305BD5-7AB9-431E-893F-73FA58600880

P2860

Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6

Item

http://www.wikidata.org/entity/Q33896527

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu