A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2. - Wikidata - awgldk - TriplyDB

A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

http://www.wikidata.org/entity/Q33896736

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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production The mitochondrial uncoupling proteins Hyperinsulinemic Hypoglycemia - The Molecular Mechanisms Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein.Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion Both ischemic preconditioning and ghrelin administration protect hippocampus from ischemia/reperfusion and upregulate uncoupling protein-2 ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.The regulation and turnover of mitochondrial uncoupling proteins.Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages Mitochondrial uncoupling and lifespan.Mitochondrial uncoupling protein-2 (UCP2) mediates leptin protection against MPP+ toxicity in neuronal cells.High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance.Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions.Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model.Variation in the uncoupling protein 2 and 3 genes and human performance.By Regulating Mitochondrial Ca2+-Uptake UCP2 Modulates Intracellular Ca2+.Uncoupling protein homologs may provide a link between mitochondria, metabolism and lifespan Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells.Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion.UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis Uncoupling proteins: role in insulin resistance and insulin insufficiency Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles.Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension.Congenital hyperinsulinism: current trends in diagnosis and therapy.Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2.Mitochondrial ROS signaling in organismal homeostasis.Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians.Leishmania donovani restricts mitochondrial dynamics to enhance miRNP stability and target RNA repression in host macrophages.Repetitive transient depolarizations of the inner mitochondrial membrane induced by proton pumping.Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.Mutational analysis of the UCP2 core promoter and relationships of variants with obesity.

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P2860

A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

http://www.wikidata.org/entity/Q33896736

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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A significant portion of mitoc ...... depends on expression of UCP2.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

A significant portion of mitoc ...... depends on expression of UCP2.

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P2093

Bradford B Lowell

http://www.w3.org/2001/XMLSchema#string

Chen-Yu Zhang

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Stefan Krauss

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P2860

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Mechanism and evolution of the uncoupling protein of brown adipose tissue

In vivo effects of uncoupling protein-3 gene disruption on mitochondrial energy metabolism.

Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism.

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

Mitochondrial proton leak and the uncoupling protein 1 homologues.

Cellular energy utilization and molecular origin of standard metabolic rate in mammals.

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

The physiological significance of mitochondrial proton leak in animal cells and tissues.

P304

118-122

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10.1073/PNAS.012410699

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1

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99

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2001-12-26T00:00:00Z

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11600438

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11756659

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117524

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