SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase - Wikidata - awgldk - TriplyDB

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

http://www.wikidata.org/entity/Q33900644

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What's new in enzymatic halogenations Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH)Structural Analysis of an Open Active Site Conformation of Nonheme Iron Halogenase CytC3 Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan Halomethane Biosynthesis: Structure of a SAM-Dependent Halide Methyltransferase from Arabidopsis thaliana Conformational switch triggered by -ketoglutarate in a halogenase of curacin A biosynthesis Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5 Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases Inhibition of 2-oxoglutarate dependent oxygenases Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.Mass spectral molecular networking of living microbial colonies.Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases.A new family of iron-dependent halogenases acts on freestanding substrates.Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase.Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase Elucidation of the Fe(IV)=O intermediate in the catalytic cycle of the halogenase SyrB2.Metamorphic enzyme assembly in polyketide diversification.Identification of the syr-syp box in the promoter regions of genes dedicated to syringomycin and syringopeptin production by Pseudomonas syringae pv. syringae B301D Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus.Chlorosulfolipids: structure, synthesis, and biological relevance.Diversity of nonribosomal peptide synthetases involved in the biosynthesis of lipopeptide biosurfactants.Non-heme Fe(IV)-oxo intermediates.Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis.Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.A sea of biosynthesis: marine natural products meet the molecular age.Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase.Expanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil.Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2.Cloning and characterization of the biosynthetic gene cluster for kutznerides.Nonribosomal Peptide Synthesis-Principles and Prospects.Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides Structural basis for the enantiospecificities of R- and S-specific phenoxypropionate/alpha-ketoglutarate dioxygenases.Iron(II)-catalyzed asymmetric intramolecular olefin aminochlorination using chloride ion.Variations of the 2-His-1-carboxylate theme in mononuclear non-heme FeII oxygenases.Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology Substrate placement influences reactivity in non-heme Fe(II) halogenases and hydroxylases.Halogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans.

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P2860

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

http://www.wikidata.org/entity/Q33900644

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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Proceedings of the National Academy of Sciences of the United States of America

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SyrB2 in syringomycin E biosyn ...... e- and O2-dependent halogenase

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P2093

Christopher T Walsh

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Frédéric H Vaillancourt

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Jun Yin

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P2860

Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol

FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit.

Isolation, structure determination, and biological activity of Lyngbyabellin A from the marine cyanobacterium lyngbya majuscula.

Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.

The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes.

A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.

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10111-10116

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scholarly article

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10.1073/PNAS.0504412102

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29

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102

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2005-07-07T00:00:00Z

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7742795

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16002467

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1177402

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