The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation.
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HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxisThe Hotdog fold: wrapping up a superfamily of thioesterases and dehydratasesStructure--function relationships in HIV-1 Nef.Predicted mouse peroxisome-targeted proteins and their actual subcellular locationsSeparation of human immunodeficiency virus type 1 replication from nef-mediated pathogenesis in the human thymusSelf-association of the Lentivirus protein, NefDynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef.Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptorsNef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.Nef alleles from human immunodeficiency virus type 1-infected long-term-nonprogressor hemophiliacs with or without late disease progression are defective in enhancing virus replication and CD4 down-regulation.The peroxisome: orchestrating important developmental decisions from inside the cell.Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variableIntegration of peroxisomes into an endomembrane system that governs cellular aging.Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.Viral proteomics.Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain.A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.Mechanisms of HIV-1 Nef function and intracellular signaling.Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.Peroxisomes and the antiviral responses of mammalian cells.Peroxisome-mitochondria interplay and disease.Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assaysHIV-1 Nef: Taking Control of Protein Trafficking.Identification of a type 1 peroxisomal targeting signal in a viral protein and demonstration of its targeting to the organelle.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Type III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling.MICOP: Maximal information coefficient-based oscillation prediction to detect biological rhythms in proteomics data.Peroxisome Dynamics: Molecular Players, Mechanisms, and (Dys)functions
P2860
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P2860
The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
The human thioesterase II prot ...... tical for CD4 down-regulation.
@ast
The human thioesterase II prot ...... tical for CD4 down-regulation.
@en
type
label
The human thioesterase II prot ...... tical for CD4 down-regulation.
@ast
The human thioesterase II prot ...... tical for CD4 down-regulation.
@en
prefLabel
The human thioesterase II prot ...... tical for CD4 down-regulation.
@ast
The human thioesterase II prot ...... tical for CD4 down-regulation.
@en
P2093
P2860
P356
P1476
The human thioesterase II prot ...... tical for CD4 down-regulation.
@en
P2093
P2860
P304
23097-23105
P356
10.1074/JBC.M000536200
P407
P577
2000-07-01T00:00:00Z