Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034.

Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034.

Item
http://www.wikidata.org/entity/Q33911559
Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibitPemetrexed for advanced stage nonsquamous non-small cell lung cancer: latest evidence about its extended use and outcomesPhase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over theUsp9x- and Noxa-mediated Mcl-1 downregulation contributes to pemetrexed-induced apoptosis in human non-small-cell lung cancer cellsAdvances in malignant pleural mesothelioma therapy: targeting EphA2 a novel approach.Metformin synergistic pemetrexed suppresses non-small-cell lung cancer cell proliferation and invasion in vitro.5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887.Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells.Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways.
P2860

Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034.

Item
http://www.wikidata.org/entity/Q33911559
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@ast
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@en
type
label
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@ast
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@en
prefLabel
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@ast
Pharmacokinetic and pharmacody ...... ltransferase inhibitor AG2034.
@en
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
Pharmacokinetic and pharmacody ...... yltransferase inhibitor AG2034
@en
P2093
P304
P31
P407
P433
P478
P577
P698