Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
about
One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.The human proton-coupled folate transporter: Biology and therapeutic applications to cancer.6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human TumorsTumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosyStructural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Antifolate agents: a patent review (2010 - 2013).The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer.
P2860
Q33618935-002EEB23-FADF-4797-9FF6-D16B01DDF9FEQ34297931-F5479C32-BCFA-456C-8D78-86DF1C7C051FQ36467564-C80EA142-DE81-4E3F-8CEC-E9A5C0951F17Q37246257-FBBBDFEF-E490-48A4-8504-0528E50BEAE8Q37587969-C7D5F460-66BD-4C82-9009-D2D8971698E8Q37663377-79479FBC-CEDD-46D5-A0BB-62CD4AF82DF2Q38198160-92687A9F-1885-43C2-9630-D20DC6B8C48AQ50062142-CEAECA30-18EB-492E-A096-9F54DD63E288
P2860
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@ast
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@en
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@nl
type
label
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@ast
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@en
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@nl
prefLabel
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@ast
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@en
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@nl
P2093
P2860
P356
P1476
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
@en
P2093
H L McLeod
L Paradiso
M Pitsiladis
Y Pithavala
P2860
P2888
P304
P356
10.1054/BJOC.2000.1601
P407
P577
2001-02-02T00:00:00Z
P5875
P6179
1042784193