Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. - Wikidata - awgldk - TriplyDB

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

http://www.wikidata.org/entity/Q33913278

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miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability The Ccr4-Not complex is a key regulator of eukaryotic gene expression Ccr4-Not complex: the control freak of eukaryotic cells Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems The Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality Control Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex Structure and assembly of the NOT module of the human CCR4-NOT complex Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice Insights into the structure and architecture of the CCR4-NOT complex Integrative data analysis indicates an intrinsic disordered domain character of Argonaute-binding motifs.Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Genome-wide assessment of AU-rich elements by the AREScore algorithm.Sexual and asexual oogenesis require the expression of unique and shared sets of genes in the insect Acyrthosiphon pisum.HPat a decapping activator interacting with the miRNA effector complex.A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis CUP promotes deadenylation and inhibits decapping of mRNA targets.The Not5 subunit of the ccr4-not complex connects transcription and translation Multi-functional regulation of 4E-BP gene expression by the Ccr4-Not complex Developmental functions of piRNAs and transposable elements: a Drosophila point-of-view Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition.GW-Bodies and P-Bodies Constitute Two Separate Pools of Sequestered Non-Translating RNAs CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins Telomeric repeat silencing in germ cells is essential for early development in Drosophila.Coordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during development Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease The architecture of the Schizosaccharomyces pombe CCR4-NOT complex The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction.Kiss your tail goodbye: the role of PARN, Nocturnin, and Angel deadenylases in mRNA biology.mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos.

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P2860

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

http://www.wikidata.org/entity/Q33913278

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2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

@ast

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

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type

label

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

@ast

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

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prefLabel

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

@ast

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

@en

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Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation

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Andrea Sinz

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Aymeric Chartier

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Christian Ihling

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Claudia Temme

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Elisabeth Kremmer

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Martine Simonelig

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P2860

Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

Functional organization of the yeast proteome by systematic analysis of protein complexes

CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.

Conservation of the deadenylase activity of proteins of the Caf1 family in human

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

The BTG2 protein is a general activator of mRNA deadenylation

The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation

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10.1261/RNA.2145110

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