Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability. - Wikidata - awgldk - TriplyDB

Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability.

Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability.

http://www.wikidata.org/entity/Q33916958

about

A possible role for integrin signaling in diffuse axonal injury Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival From mechanical force to RhoA activation Rho GAPs and GEFs: controling switches in endothelial cell adhesion Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells Microtubule dynamics control HGF-induced lung endothelial barrier enhancement Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.Finite-element modeling of viscoelastic cells during high-frequency cyclic strain Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury.Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury.Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.Role of microtubules in attenuation of PepG-induced vascular endothelial dysfunction by atrial natriuretic peptide.Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.Asef controls vascular endothelial permeability and barrier recovery in the lung.Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation.Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6.Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.Novel role of stathmin in microtubule-dependent control of endothelial permeability.Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton.Role of Krev Interaction Trapped-1 in Prostacyclin-Induced Protection against Lung Vascular Permeability Induced by Excessive Mechanical Forces and Thrombin Receptor Activating Peptide 6.Endothelial barrier disruption and recovery is controlled by substrate stiffness.Mechanical forces stimulate endothelial microparticle generation via caspase-dependent apoptosis-independent mechanism Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch.Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism.GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism.Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.Regulation of paracellular permeability: factors and mechanisms.Regulation of the endothelial barrier function: a filum granum of cellular forces, Rho-GTPase signaling and microenvironment.

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Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability.

http://www.wikidata.org/entity/Q33916958

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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type

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Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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prefLabel

Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

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AJPLUNG.00263.2009

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American Journal of Physiology - Lung Cellular and Molecular Physiology

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Mechanotransduction by GEF-H1 ...... ular endothelial permeability.

@en

P2093

Anna A Birukova

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Bakhtiyor Yakubov

http://www.w3.org/2001/XMLSchema#string

Ivan Cokic

http://www.w3.org/2001/XMLSchema#string

Junjie Xing

http://www.w3.org/2001/XMLSchema#string

Konstantin G Birukov

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Panfeng Fu

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P2860

Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor

Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

mDia mediates Rho-regulated formation and orientation of stable microtubules

PAK4 mediates morphological changes through the regulation of GEF-H1

Biology of the p21-activated kinases

Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF.

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10.1152/AJPLUNG.00263.2009

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6

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298

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42610981

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20348280

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Mechanotransduction

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2886610

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