Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
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Insights into the structure and function of HV1 from a meta-analysis of mutation studiesThe Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma.Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle?In pursuit of an inhibitory drug for the proton channelA specialized molecular motion opens the Hv1 voltage-gated proton channel.Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7.The Hv1 proton channel responds to mechanical stimuliOn the role of water density fluctuations in the inhibition of a proton channelMolecular biology and biophysical properties of ion channel gating pores.Voltage-gated proton (H(v)1) channels, a singular voltage sensing domain.The chemistry and biology of guanidine natural products.The inhibition of voltage-gated H+ channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis.Pharmacological Modulation of Proton Channel Hv1 in Cancer Therapy: Future Perspectives.Diphenhydramine inhibits voltage-gated proton channels (Hv1) and induces acidification in leukemic Jurkat T cells- New insights into the pro-apoptotic effects of antihistaminic drugs.Voltage and pH sensing by the voltage-gated proton channel, HV1.Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy
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P2860
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@ast
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@en
type
label
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@ast
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@en
prefLabel
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@ast
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@en
P2093
P2860
P356
P1476
Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.
@en
P2093
Francesco Tombola
Iris H Kim
Liang Hong
P2860
P304
P356
10.1073/PNAS.1324012111
P407
P577
2014-05-27T00:00:00Z