Water wires in atomistic models of the Hv1 proton channel
about
Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domainsProton channel models filling the gap between experimental data and the structural rationaleMolecular dynamics simulations reveal proton transfer pathways in cytochrome C-dependent nitric oxide reductasePhilosophy of voltage-gated proton channelsVoltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) familyInsights into the structure and function of HV1 from a meta-analysis of mutation studiesThe Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma.Proton currents constrain structural models of voltage sensor activation.Hydrophobic plug functions as a gate in voltage-gated proton channels.In pursuit of an inhibitory drug for the proton channelMolecular determinants of Hv1 proton channel inhibition by guanidine derivatives.Voltage-gated proton channels.Selectivity Mechanism of the Voltage-gated Proton Channel, HV1Free-energy landscape of ion-channel voltage-sensor-domain activationGating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.Mapping the gating and permeation pathways in the voltage-gated proton channel Hv1.The pore of the voltage-gated proton channelMolecular dynamics simulations of voltage-gated cation channels: insights on voltage-sensor domain function and modulation.Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.Evolution of the voltage sensor domain of the voltage-sensitive phosphoinositide phosphatase VSP/TPTE suggests a role as a proton channel in eutherian mammalsTryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1.Resting state of the human proton channel dimer in a lipid bilayer.Construction and validation of a homology model of the human voltage-gated proton channel hHV1Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1.The Hv1 proton channel responds to mechanical stimuliOn the role of water density fluctuations in the inhibition of a proton channelEvolutionary imprint of activation: the design principles of VSDs.Mechanisms of activation of voltage-gated potassium channels.The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase.Voltage sensor of ion channels and enzymes.Identification of an HV 1 voltage-gated proton channel in insects.Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents.Rebuttal from Ashley L. Bennett and Ian Scott Ramsey.Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.CrossTalk proposal: Proton permeation through HV 1 requires transient protonation of a conserved aspartate in the S1 transmembrane helix.Voltage and pH sensing by the voltage-gated proton channel, HV1.
P2860
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P2860
Water wires in atomistic models of the Hv1 proton channel
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Water wires in atomistic models of the Hv1 proton channel
@ast
Water wires in atomistic models of the Hv1 proton channel
@en
Water wires in atomistic models of the Hv1 proton channel
@nl
type
label
Water wires in atomistic models of the Hv1 proton channel
@ast
Water wires in atomistic models of the Hv1 proton channel
@en
Water wires in atomistic models of the Hv1 proton channel
@nl
prefLabel
Water wires in atomistic models of the Hv1 proton channel
@ast
Water wires in atomistic models of the Hv1 proton channel
@en
Water wires in atomistic models of the Hv1 proton channel
@nl
P2093
P2860
P3181
P1476
Water wires in atomistic models of the Hv1 proton channel
@en
P2093
Douglas J Tobias
Eric V Schow
Francesco Tombola
J Alfredo Freites
Mona L Wood
P2860
P304
P3181
P356
10.1016/J.BBAMEM.2011.07.045
P407
P577
2012-02-01T00:00:00Z