A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.
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Neurosteroids and GABA(A) Receptor Interactions: A Focus on StressNeurosteroids: endogenous role in the human brain and therapeutic potentialsCatamenial Epilepsy: Discovery of an Extrasynaptic Molecular Mechanism for Targeted TherapyThe role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disordersNeurosteroids and their role in sex-specific epilepsiesThe biochemical anatomy of cortical inhibitory synapsesA stress steroid triggers anxiety via increased expression of α4βδ GABAA receptors in methamphetamine dependence.The influence of stress at puberty on mood and learning: role of the α4βδ GABAA receptorEstrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area.The GABAergic deficit hypothesis of major depressive disorder.Neurosteroid influences on sensitivity to ethanolGABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors.Selective early-acquired fear memories undergo temporary suppression during adolescence.Altered fear learning across development in both mouse and human.Altered localization of the δ subunit of the GABAA receptor in the thalamus of α4 subunit knockout miceDevelopment of dendritic tonic GABAergic inhibition regulates excitability and plasticity in CA1 pyramidal neurons.Excitatory synapses on dendritic shafts of the caudal basal amygdala exhibit elevated levels of GABAA receptor α4 subunits following the induction of activity-based anorexia.Ovarian cycle-linked plasticity of δ-GABAA receptor subunits in hippocampal interneurons affects γ oscillations in vivo.Characterization of neurosteroid effects on hyperpolarizing current at α4β2δ GABAA receptors.Neurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathwayDisease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis.GABAA receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental areaMidazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis.Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanismGABAA receptor trafficking-mediated plasticity of inhibitory synapses.Axonal remodeling for motor recovery after traumatic brain injury requires downregulation of γ-aminobutyric acid signaling.GABA transport modulates the ethanol sensitivity of tonic inhibition in the rat dentate gyrusAge- and sex-related characteristics of tonic GABA currents in the rat substantia nigra pars reticulata.Tyrosine phosphorylation of GABAA receptor γ2-subunit regulates tonic and phasic inhibition in the thalamus.In vitro gamma oscillations following partial and complete ablation of δ subunit-containing GABAA receptors from parvalbumin interneurons.Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse.Adolescent female rats exhibiting activity-based anorexia express elevated levels of GABA(A) receptor α4 and δ subunits at the plasma membrane of hippocampal CA1 spinesKnockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty.Pubertal onset as a critical transition for neural development and cognition.Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy statesExtrasynaptic GABA(A) receptors: their function in the CNS and implications for disease.Early cognitive experience prevents adult deficits in a neurodevelopmental schizophrenia modelFinasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis.Flumazenil decreases surface expression of α4β2δ GABAA receptors by increasing the rate of receptor internalizationSynaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines
P2860
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P2860
A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A critical role for alpha4beta ...... g deficits at puberty in mice.
@ast
A critical role for alpha4beta ...... g deficits at puberty in mice.
@en
type
label
A critical role for alpha4beta ...... g deficits at puberty in mice.
@ast
A critical role for alpha4beta ...... g deficits at puberty in mice.
@en
prefLabel
A critical role for alpha4beta ...... g deficits at puberty in mice.
@ast
A critical role for alpha4beta ...... g deficits at puberty in mice.
@en
P2093
P2860
P356
P1433
P1476
A critical role for alpha4beta ...... g deficits at puberty in mice.
@en
P2093
Ang Sherpa
Armin Stelzer
Chiye Aoki
Nicole Sabaliauskas
P2860
P304
P356
10.1126/SCIENCE.1184245
P407
P577
2010-03-01T00:00:00Z