about
Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female ratA stress steroid triggers anxiety via increased expression of α4βδ GABAA receptors in methamphetamine dependence.Effects of a low dose of ethanol in an animal model of premenstrual anxiety.Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol.Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects.Ethanol effects on GABA-gated current in a model of increased alpha4betadelta GABAA receptor expression depend on time course and preexposure to low concentrations of the drug.Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits.Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder.Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats.Progesterone withdrawal reduces paired-pulse inhibition in rat hippocampus: dependence on GABA(A) receptor alpha4 subunit upregulation.A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.Neurosteroid effects on GABAergic synaptic plasticity in hippocampusCharacterization of neurosteroid effects on hyperpolarizing current at α4β2δ GABAA receptors.GABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptorsProgesterone withdrawal increases the anxiolytic actions of gaboxadol: role of alpha4betadelta GABA(A) receptors.GABA receptors, progesterone and premenstrual dysphoric disorder.Steroid requirements for regulation of the alpha4 subunit of the GABA(A) receptor in an in vitro modelReversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at pubertyNeurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse.Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty.Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy statesFlumazenil decreases surface expression of α4β2δ GABAA receptors by increasing the rate of receptor internalizationSynaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spinesα4βδ GABAA receptors and tonic inhibitory current during adolescence: effects on mood and synaptic plasticityExpression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current.Puberty, steroids and GABA(A) receptor plasticity.Sex steroid effects on extrahypothalamic CNS. I. Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the cerebellum.Progesterone withdrawal I: pro-convulsant effects.Plasticity of the alpha4betadelta GABAA receptor.Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior.Allopregnanolone levels and symptom improvement in severe premenstrual syndrome.Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats.Estrogen administration increases neuronal responses to excitatory amino acids as a long-term effect.Ethanol administration rapidly reverses alpha4 GABAA receptor subunit upregulation following steroid exposure.Termination of pseudopregnancy in the rat produces an anxiogenic-like response that is associated with an increase in benzodiazepine receptor binding density and a decrease in GABA-stimulated chloride influx in the hippocampus.Neurosteroid administration and withdrawal alter GABAA receptor kinetics in CA1 hippocampus of female rats.A paradigm for determination of direct drug-induced modulatory alterations in Purkinje cell activity during treadmill locomotion.Sex steroid effects on extrahypothalamic CNS. II. Progesterone, alone and in combination with estrogen, modulates cerebellar responses to amino acid neurotransmitters.Progesterone withdrawal. II: insensitivity to the sedative effects of a benzodiazepine.GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
P50
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Sheryl S Smith
@es
Sheryl S. Smith
@en
Sheryl S. Smith
@nl
Sheryl S. Smith
@sl
type
label
Sheryl S Smith
@es
Sheryl S. Smith
@en
Sheryl S. Smith
@nl
Sheryl S. Smith
@sl
prefLabel
Sheryl S Smith
@es
Sheryl S. Smith
@en
Sheryl S. Smith
@nl
Sheryl S. Smith
@sl
P106
P1153
7406648319
P21
P31
P496
0000-0003-4308-3267
P569
2000-01-01T00:00:00Z