Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
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Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoesRegulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblastsThe effects of aging on gene expression in the hypothalamus and cortex of miceEvolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebratesExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysRegulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathwayCollapse of proteostasis represents an early molecular event in Caenorhabditis elegans agingRegulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegansNew genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen.Functional genomic analysis of C. elegans moltingMetabolic homeostasis as the cornerstone of agingOn the cause of aging and control of lifespan: heterogeneity leads to inevitable damage accumulation, causing aging; control of damage composition and rate of accumulation define lifespanTau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy modeldbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental ArrestReduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegansdaf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespanGamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activityTwo membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signalingDeletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespanA mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegansThe evolution and origin of animal Toll-like receptor signaling pathway revealed by network-level molecular evolutionary analysesBrain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanismA decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegansETS-4 is a transcriptional regulator of life span in Caenorhabditis elegansInsulin, aging, and the brain: mechanisms and implicationsThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterCell-nonautonomous regulation of C. elegans germ cell death by kri-1Integrating the stress response: lessons for neurodegenerative diseases from C. elegansG-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptorThe cell-non-autonomous nature of electron transport chain-mediated longevityLessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism.Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53.Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses.Running on empty: how p53 controls INS/IGF signaling and affects life spanPI3K integrates the action of insulin and leptin on hypothalamic neurons.Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans.Stimulation of movement in a quiescent, hibernation-like form of Caenorhabditis elegans by dopamine signalingCounterbalance between BAG and URX neurons via guanylate cyclases controls lifespan homeostasis in C. elegansHypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRHDauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.
P2860
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P2860
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@ast
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@en
type
label
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@ast
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@en
prefLabel
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@ast
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@en
P2093
P1433
P1476
Regulation of C. elegans life-span by insulinlike signaling in the nervous system.
@en
P2093
P304
P356
10.1126/SCIENCE.290.5489.147
P407
P577
2000-10-01T00:00:00Z