Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells.
about
Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell linesRestoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier functionMitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate.Biology of the major facilitative folate transporters SLC19A1 and SLC46A1Biochemical and molecular mechanisms of folate transport in rat pancreas; interference with ethanol ingestionFunctional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat modelFolate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis.Molecular and biochemical characterization of folate transport proteins in retinal Müller cellsMechanisms of membrane transport of folates into cells and across epithelia.Linking vitamin B1 with cancer cell metabolismAugmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphateFolate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors.The intestinal absorption of folates.Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.A putative thiamine transport protein is a receptor for feline leukemia virus subgroup AStructure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter.Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.Resistance to antifolates.Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathwayContribution of tumoral and host solute carriers to clinical drug response.A high-affinity and specific carrier-mediated mechanism for uptake of thiamine pyrophosphate by human colonic epithelial cells.Expression Profiling of Solute Carrier Gene Families at the Blood-CSF Barrier.Inhibition of the proton-coupled folate transporter (PCFT-SLC46A1) by bicarbonate and other anions.Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport.Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells.Other mechanisms to explain the role of reduced folate carrier in cancer.Exome sequencing reveals mutated SLC19A3 in patients with an early-infantile, lethal encephalopathy.Quantitation of plasma thiamine, related metabolites and plasma protein oxidative damage markers in children with autism spectrum disorder and healthy controls.Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats.The Warburg Effect as a Type B Lactic Acidosis in a Patient With Acute Myeloid Leukemia: A Diagnostic Challenge for Clinicians.The adaptive regulation of thiamine pyrophosphokinase-1 facilitates malignant growth during supplemental thiamine conditions
P2860
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P2860
Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Impact of the reduced folate c ...... ites in murine leukemia cells.
@ast
Impact of the reduced folate c ...... ites in murine leukemia cells.
@en
type
label
Impact of the reduced folate c ...... ites in murine leukemia cells.
@ast
Impact of the reduced folate c ...... ites in murine leukemia cells.
@en
prefLabel
Impact of the reduced folate c ...... ites in murine leukemia cells.
@ast
Impact of the reduced folate c ...... ites in murine leukemia cells.
@en
P2093
P2860
P356
P1476
Impact of the reduced folate c ...... ites in murine leukemia cells.
@en
P2093
P2860
P304
P356
10.1074/JBC.M007919200
P407
P577
2001-01-01T00:00:00Z