Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
about
Killing cells by targeting mitosisCDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth.Modulation of glycogen synthase kinase-3β following TRAIL combinatorial treatment in cancer cells.Oxygen regulates molecular mechanisms of cancer progression and metastasis.Hypoxic inactivation of glycogen synthase kinase-3β promotes gastric tumor growth and angiogenesis by facilitating hypoxia-inducible factor-1 signaling.Sangivamycin-like molecule 6 exhibits potent anti-multiple myeloma activity through inhibition of cyclin-dependent kinase-9HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression.Synthesis, Preferentially Hypoxic Apoptosis and Anti-Angiogenic Activity of 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide Bearing Alkyl Linkers with a 3-Amino-1,2,4-Benzotriazine-1-Oxide Moiety.The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia.Hypoxia-inducible factor-1α and its role in the proliferation of retinoblastoma cells.Targeting CDK4/6 to oppose hypoxia-mediated therapeutic resistance.
P2860
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P2860
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@ast
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@en
type
label
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@ast
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@en
prefLabel
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@ast
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@en
P2093
P2860
P1433
P1476
Overcoming hypoxia-induced apo ...... inhibition of GSK-3β and CDK1.
@en
P2093
Colin J Daniel
David I H Jee
David T Dicker
Emma E Furth
J Judy Liu
J Martin Brown
Jay F Dorsey
Joshua E Allen
Kageaki Kuribayashi
Lori S Hart
P2860
P304
P356
10.1158/0008-5472.CAN-11-1383
P407
P577
2011-06-06T00:00:00Z