Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.
about
Immunity to retroviral infection: the Friend virus modelOrigin and rapid evolution of a novel murine erythroleukemia virus of the spleen focus-forming virus family.An array of novel murine spleen focus-forming viruses that activate the erythropoietin receptor.Lymphocyte deficiencies increase susceptibility to friend virus-induced erythroleukemia in Fv-2 genetically resistant miceRole of interleukin-4 (IL-4), IL-12, and gamma interferon in primary and vaccine-primed immune responses to Friend retrovirus infectionFLI-1 inhibits differentiation and induces proliferation of primary erythroblasts.Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation.Both the polycythemia- and anemia-inducing strains of Friend spleen focus-forming virus induce constitutive activation of the Raf-1/mitogen-activated protein kinase signal transduction pathwayHelix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus.Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in miceFriend Spleen Focus-Forming Virus Activates the Tyrosine Kinase sf-Stk and the Transcription Factor PU.1 to Cause a Multi-Stage Erythroleukemia in Mice.Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia.Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein.Recovery from Friend disease in mice with reduced major histocompatibility complex class I expression.Selectable retrovirus vectors encoding Friend virus gp55 or erythropoietin induce polycythemia with different phenotypic expression and disease progression.A Friend virus mutant that overcomes Fv-2rr host resistance encodes a small glycoprotein that dimerizes, is processed to cell surfaces, and specifically activates erythropoietin receptors.A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation.Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin.Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma.Platelet-derived growth factor receptor can mediate tumorigenic transformation by the bovine papillomavirus E5 protein.Mutations in the env gene of friend spleen focus-forming virus overcome Fv-2r-mediated resistance to Friend virus-induced erythroleukemia.The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein.Role of the PU.1 transcription factor in controlling differentiation of Friend erythroleukemia cells.Immunoglobulin heavy-chain and CD3 delta-chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells.Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cells.The activated Mlvi-4 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas encodes an env/Mlvi-4 fusion protein.Erythropoietin receptor (EpoR)-dependent mitogenicity of spleen focus-forming virus correlates with viral pathogenicity and processing of env protein but not with formation of gp52-EpoR complexes in the endoplasmic reticulum.Amplified and tissue-directed expression of retroviral vectors using ping-pong techniques.Differential STAT5 signaling by ligand-dependent and constitutively active cytokine receptors.Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function.Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.Clonal analysis of erythropoietin stimulated J2E cells reveals asynchrony during terminal differentiation.Pathogenicity of a mutant friend spleen focus-forming virus encoding an Env-like membrane glycoprotein (gp55) with substitution by a xenotropic murine leukemia virus Env gp70 sequence.Effects of type I interferons on Friend retrovirus infection.
P2860
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P2860
Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.
description
1990 nî lūn-bûn
@nan
1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@ast
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@en
type
label
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@ast
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@en
prefLabel
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@ast
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@en
P2093
P2860
P356
P1476
Activation of erythropoietin r ...... murine Fv-2r resistance gene.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.24.9985
P407
P577
1990-12-01T00:00:00Z