Silibinin can induce differentiation as well as enhance vitamin D3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors.
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Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D₃The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyThe Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cellsInhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells.The MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage.Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells.Prodifferentiation Activity of Novel Vitamin D₂ Analogs PRI-1916 and PRI-1917 and Their Combinations with a Plant Polyphenol in Acute Myeloid Leukemia Cells.BRAF signals to pro-apoptotic BIM to enhance AraC cytotoxicity induced in AML cells by Vitamin D-based differentiation agents.The role of VDR and BIM in potentiation of cytarabine-induced cell death in human AML blasts.Established Human Cell Lines as Models to Study Anti-leukemic Effects of Flavonoids.Cell-Type-Specific Effects of Silibinin on Vitamin D-Induced Differentiation of Acute Myeloid Leukemia Cells Are Associated with Differential Modulation of RXRα Levels.RB in breast cancer: differential effects in estrogen receptor-positive and estrogen receptor-negative disease.Silibinin: an old drug for hematological disorders.
P2860
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P2860
Silibinin can induce differentiation as well as enhance vitamin D3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Silibinin can induce different ...... related transcription factors.
@ast
Silibinin can induce different ...... related transcription factors.
@en
type
label
Silibinin can induce different ...... related transcription factors.
@ast
Silibinin can induce different ...... related transcription factors.
@en
prefLabel
Silibinin can induce different ...... related transcription factors.
@ast
Silibinin can induce different ...... related transcription factors.
@en
P2093
P2860
P356
P1476
Silibinin can induce different ...... related transcription factors.
@en
P2093
George P Studzinski
Jing Zhang
Jonathan S Harrison
Michael Danilenko
Milan Uskokovic
P2860
P304
P356
10.1002/HON.929
P577
2010-09-01T00:00:00Z