AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function
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Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylationMolecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST ComplexThe CW domain, a new histone recognition module in chromatin proteinsLSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 DemethylationStructure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1bStructural insight into substrate recognition by histone demethylase LSD2/KDM1bTranscriptional regulation of the albumin gene depends on the removal of histone methylation marks by the FAD-dependent monoamine oxidase lysine-specific demethylase 1 in HepG2 human hepatocarcinoma cellsHuman LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.Small-molecular modulators of cancer-associated epigenetic mechanisms.Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: implications for adoptive immunotherapy of cancerFLOWERING LOCUS T has higher protein mobility than TWIN SISTER OF FTHow microRNAs facilitate reprogramming to pluripotency.The MTA family proteins as novel histone H3 binding proteins.Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners.Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells.Catalytic-independent roles of UTX-1 in C. elegans development.The MORC family: new epigenetic regulators of transcription and DNA damage response.Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.Lysine methylation: beyond histones.An overview of phenylcyclopropylamine derivatives: biochemical and biological significance and recent developments.Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells.Targeting Histone Demethylases: A New Avenue for the Fight against Cancer.KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.LSD1 inhibitors: a patent review (2010-2015).Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases.O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview.Lysine-specific demethylase 2 suppresses lipid influx and metabolism in hepatic cells.Low activity of LSD1 elicits a pro-inflammatory gene expression profile in riboflavin-deficient human T Lymphoma Jurkat cells.Crosstalk between TGF-β signaling and epigenome.Jak/Stat3 signaling promotes somatic cell reprogramming by epigenetic regulation.KDM1A microenvironment, its oncogenic potential, and therapeutic significance.Prominent role of histone lysine demethylases in cancer epigenetics and therapy
P2860
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P2860
AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@ast
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@en
type
label
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@ast
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@en
prefLabel
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@ast
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@en
P2093
P2860
P356
P1433
P1476
AOF1 is a histone H3K4 demethy ...... ndependent repression function
@en
P2093
Jiemin Wong
Kenichi Yamane
M David Stewart
Shankang Qi
P2860
P2888
P304
P356
10.1038/CR.2010.12
P50
P577
2010-01-26T00:00:00Z