Melanocortin-4 receptor gene variant I103 is negatively associated with obesity - Wikidata - awgldk - TriplyDB

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

http://www.wikidata.org/entity/Q33930734

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Common variants near MC4R are associated with fat mass, weight and risk of obesity Obesity genetics in mouse and human: back and forth, and back again Genetic & epigenetic approach to human obesity Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups Practical Experience of the Application of a Weighted Burden Test to Whole Exome Sequence Data for Obesity and Schizophrenia Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity.Unraveling the genetics of human obesity.Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia Prevalence of pathogenetic MC4R mutations in Italian children with early onset obesity, tall stature and familial history of obesity.Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study.Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).Prevalence of loss-of-function FTO mutations in lean and obese individuals Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions Recent progress in the genetics of common obesity Eating disorders: the current status of molecular genetic research.From monogenic to polygenic obesity: recent advances.Investigation of a genome wide association signal for obesity: synthetic association and haplotype analyses at the melanocortin 4 receptor gene locus.Analysis of the SIM1 contribution to polygenic obesity in the French population Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery.Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.In silico mutagenesis: a case study of the melanocortin 4 receptor Molecular basis of obesity: current status and future prospects Genetics of Obesity: What have we Learned?Role of genetic susceptibility in development of treatment-related adverse outcomes in cancer survivors The MC4R(I251L) allele is associated with better metabolic status and more weight loss after gastric bypass surgery.Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons Medical sequencing at the extremes of human body mass.Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.Allelic variants of the Melanocortin 4 receptor (MC4R) gene in a South African study group On the replication of genetic associations: timing can be everything!Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.Molecular genetic aspects of weight regulation.Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight, or both.The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals.Mouse models for the central melanocortin system.Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.

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Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

http://www.wikidata.org/entity/Q33930734

description

2004 nî lūn-bûn

@nan

2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@ast

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@en

type

label

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@ast

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@en

prefLabel

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@ast

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@en

P1433

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American Journal of Human Genetics

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Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

@en

P2093

Astrid Dempfle

http://www.w3.org/2001/XMLSchema#string

Caren Vollmert

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Claudia Hess

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H-Erich Wichmann

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Heike Biebermann

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Helmut Schäfer

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Kathrin Reichwald

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Stephan Herpertz

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Thomas Gudermann

http://www.w3.org/2001/XMLSchema#string

Winfried Siffert

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P2860

Are rare variants responsible for susceptibility to complex diseases?

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction

PedCheck: a program for identification of genotype incompatibilities in linkage analysis

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test

Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

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572-581

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scholarly article

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10.1086/382490

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3

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74

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Matthias Platzer

Johannes Hebebrand

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2004-02-17T00:00:00Z

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8688295

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14973783

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1193776

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