Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. - Wikidata - awgldk - TriplyDB

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.

http://www.wikidata.org/entity/Q33934565

about

Steroid receptor coactivators: servants and masters for control of systems metabolism SRC-3 has a role in cancer other than as a nuclear receptor coactivator.Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism Endocrine-disrupting chemicals and fatty liver disease.Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC‑3 knockout mice.Translating extranuclear steroid receptor signaling to clinical medicine.Extranuclear estrogen receptor's roles in physiology: lessons from mouse models Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo.Nuclear receptor coactivators: master regulators of human health and disease.Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis.NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer.Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis Steroid receptor coactivator-3 as a potential molecular target for cancer therapy.Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family.Steroid receptor coactivator (SRC) family: masters of systems biology.Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding.Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors.Steroid receptor co-activator-3 promotes osteosarcoma progression through up-regulation of FoxM1.Analysis of the human endogenous coregulator complexome.Metastasis-associated protein 1 is an upstream regulator of DNMT3a and stimulator of insulin-growth factor binding protein-3 in breast cancer.SRC3 expressed in BMSCs promotes growth and migration of multiple myeloma cells by regulating the expression of Cx43.

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P2860

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.

http://www.wikidata.org/entity/Q33934565

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Reprogramming the posttranslat ...... in mammalian systems biology.

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Reprogramming the posttranslat ...... in mammalian systems biology.

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Reprogramming the posttranslat ...... in mammalian systems biology.

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Reprogramming the posttranslat ...... in mammalian systems biology.

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PNAS.1005262107

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Proceedings of the National Academy of Sciences of the United States of America

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Reprogramming the posttranslat ...... h in mammalian systems biology

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P2093

Brian York

http://www.w3.org/2001/XMLSchema#string

Chundong Yu

http://www.w3.org/2001/XMLSchema#string

Jianming Xu

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Jørn V Sagen

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Milton Finegold

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Ray-Chang Wu

http://www.w3.org/2001/XMLSchema#string

Zhaoliang Liu

http://www.w3.org/2001/XMLSchema#string

P2860

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family

ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance.

The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes.

Nuclear receptor coregulators and human disease.

Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.

Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression.

The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.

Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation.

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11122-11127

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scholarly article

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10.1073/PNAS.1005262107

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24

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107

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Bryan C Nikolai

Bert W. O'Malley

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2010-06-01T00:00:00Z

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44660078

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20534466

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