ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. - Wikidata - awgldk - TriplyDB

ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance.

ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance.

http://www.wikidata.org/entity/Q34345868

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The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 The transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypes Estrogen receptor alpha controls a gene network in luminal-like breast cancer cells comprising multiple transcription factors and microRNAs Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 Noncoding RNA in oncogenesis: a new era of identifying key players Nuclear receptor coregulators: modulators of pathology and therapeutic targets To live or let die - complexity within the E2F1 pathway Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor SRC-3 has a role in cancer other than as a nuclear receptor coactivator.Prognostic relevance of AIB1 (NCoA3) amplification and overexpression in breast cancer.Antiestrogens: structure-activity relationships and use in breast cancer treatment Nuclear receptor coactivators: the key to unlock chromatin Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells Prior Adjuvant Tamoxifen Treatment in Breast Cancer Is Linked to Increased AIB1 and HER2 Expression in Metachronous Contralateral Breast Cancer The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype Regulation of hormonal therapy resistance by cell cycle machinery.Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α.Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands.Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs)Cadmium promotes breast cancer cell proliferation by potentiating the interaction between ERalpha and c-Jun.Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription.Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor.Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02.E2F activators signal and maintain centrosome amplification in breast cancer cells.Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice.Promoting E2F1-mediated apoptosis in oestrogen receptor-α-negative breast cancer cells Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family

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ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance.

http://www.wikidata.org/entity/Q34345868

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2004 nî lūn-bûn

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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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MCB.24.12.5157-5171.2004

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Molecular and Cellular Biology

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ACTR/AIB1 functions as an E2F1 ...... n and antiestrogen resistance.

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P2093

Alina Rabinovich

http://www.w3.org/2001/XMLSchema#string

Hong-Wu Chen

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June X Zou

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Maggie C Louie

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P2860

Molecular determinants of the estrogen receptor-coactivator interface

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

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5157-5171

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scholarly article

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10.1128/MCB.24.12.5157-5171.2004

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12

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24

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2004-06-01T00:00:00Z

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8536599

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15169882

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419858

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