Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates.
about
The cysteine protease cathepsin B is a key drug target and cysteine protease inhibitors are potential therapeutics for traumatic brain injuryCellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationFrom rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemiaHsp70.1 and related lysosomal factors for necrotic neuronal deathThe atypical calpains: evolutionary analyses and roles in Caenorhabditis elegans cellular degenerationImplications of CAD and DNase II in ischemic neuronal necrosis specific for the primate hippocampusTrypanosoma cruzi response to sterol biosynthesis inhibitors: morphophysiological alterations leading to cell deathIschemic Postconditioning as a Novel Avenue to Protect against Brain Injury after StrokeCalpain immunoreactivity and morphological damage in chinchilla inner ears after carboplatinActivation of cell death pathways in the inner ear of the aging CBA/J mouse.Intracellular two-phase Ca2+ release and apoptosis controlled by TRP-ML1 channel activity in coronary arterial myocytes.Differential proteomics reveals multiple components in retrogradely transported axoplasm after nerve injury.Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus.Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats.Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.Proteases inhibition assessment on PC12 and NGF treated cells after oxygen and glucose deprivation reveals a distinct role for aspartyl proteases.Visualizing cell death in experimental focal cerebral ischemia: promises, problems, and perspectives.Death by necrosis. Uncontrollable catastrophe, or is there order behind the chaos?Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans.Heat shock protein 70.1 (Hsp70.1) affects neuronal cell fate by regulating lysosomal acid sphingomyelinase.Small heat-shock proteins protect from heat-stroke-associated neurodegeneration.Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans.Dying for a cause: invertebrate genetics takes on human neurodegeneration.Adult neuron survival strategies--slamming on the brakes.Mechanisms of neural cell death: implications for development of neuroprotective treatment strategiesProteolytic mechanisms in necrotic cell death and neurodegeneration.Caspase inhibitors as neuroprotective agents.Implication of calpain in neuronal apoptosis. A possible regulation of Alzheimer's disease.Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.Involvement of calpain activation in neurodegenerative processes.Calpains and their multiple roles in diabetes mellitus.Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration.In vivo animal stroke models: a rationale for rodent and non-human primate models.Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis.Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death.Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responsesCalpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration.Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia.Apoptosis of hippocampal pyramidal neurons is virus independent in a mouse model of acute neurovirulent picornavirus infectionModeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans.
P2860
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P2860
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Implication of cysteine protea ...... ic neuronal death of primates.
@ast
Implication of cysteine protea ...... ic neuronal death of primates.
@en
type
label
Implication of cysteine protea ...... ic neuronal death of primates.
@ast
Implication of cysteine protea ...... ic neuronal death of primates.
@en
prefLabel
Implication of cysteine protea ...... ic neuronal death of primates.
@ast
Implication of cysteine protea ...... ic neuronal death of primates.
@en
P1476
Implication of cysteine protea ...... ic neuronal death of primates.
@en
P2093
Yamashima T
P304
P356
10.1016/S0301-0082(00)00006-X
P577
2000-10-01T00:00:00Z