Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells.

Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells.

Item
http://www.wikidata.org/entity/Q33942430
Cucurbitacin E induces cell cycle G2/M phase arrest and apoptosis in triple negative breast cancerIL-6 stimulates STAT3 and Pim-1 kinase in pancreatic cancer cell lines.Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cellsActivation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells.Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.JSI124 inhibits breast cancer cell growth by suppressing the function of B cells via the downregulation of signal transducer and activator of transcription 3.Cell cycle arrest and apoptosis induced by Porphyromonas gingivalis requires JNK- and p53-mediated p38 activation in human trophoblasts.The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS.Antiangiogenic effects of cucurbitacin-I.
P2860

Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells.

Item
http://www.wikidata.org/entity/Q33942430
description
2011 nî lūn-bûn
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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2011 թվականի հունիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@ast
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@en
type
label
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@ast
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@en
prefLabel
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@ast
Cucurbitacin-I (JSI-124) activ ...... le arrest in B leukemic cells.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P6179
P698
P921
P932
P356
P1433
P1476
Cucurbitacin-I (JSI-124) activ ...... cle arrest in B leukemic cells
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P6179
P698
P921
P932