Regulation of the pancreatic pro-endocrine gene neurogenin3.
about
Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDMBasic helix-loop-helix transcription factors and enteroendocrine cell differentiationRepression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivoHes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanismsGenome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyStem Cells in the Intestine: Possible Roles in Pathogenesis of Irritable Bowel SyndromeNotch Signaling in Pancreatic DevelopmentTranscription factor regulation of pancreatic organogenesis, differentiation and maturationTarget gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressorsIdentification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional networkEarly pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complexHes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland developmentThe Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.Precursor cells in mouse islets generate new beta-cells in vivo during aging and after islet injury.Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancersLack of TCF2/vHNF1 in mice leads to pancreas agenesisNeurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate.Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell developmentThe insulin gene in diabetes.A mouse model for monitoring islet cell genesis and developing therapies for diabetesEctopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.OVO homologue-like 1 (Ovol1) transcription factor: a novel target of neurogenin-3 in rodent pancreas.Sox9: a master regulator of the pancreatic program.Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells.Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitorsThe Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice.Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.Differential levels of Neurod establish zebrafish endocrine pancreas cell fates.The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas.The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.Estradiol meets notch signaling in developing neurons.Sox9 coordinates a transcriptional network in pancreatic progenitor cellsA Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiationFeedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6.The potential for stem cell therapy in diabetes.
P2860
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P2860
Regulation of the pancreatic pro-endocrine gene neurogenin3.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@ast
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@en
type
label
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@ast
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@en
prefLabel
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@ast
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@en
P2093
P1433
P1476
Regulation of the pancreatic pro-endocrine gene neurogenin3.
@en
P2093
M S German
R G Mirmira
P304
P356
10.2337/DIABETES.50.5.928
P407
P577
2001-05-01T00:00:00Z