Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. - Wikidata - awgldk - TriplyDB

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.

http://www.wikidata.org/entity/Q34361184

about

Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation Selective gene expression by rat gastric corpus epithelium Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation Insulin-secreting β cells require a post-genomic concept Stomach development, stem cells and disease Organoid Models of Human Gastrointestinal Development and Disease Lineage selection and plasticity in the intestinal crypt Epigenetic silencing of Notch signaling in gastrointestinal cancers Generating human intestinal tissues from pluripotent stem cells to study development and disease Arx is required for normal enteroendocrine cell development in mice and humans Direct regulation of intestinal fate by Notch Delta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell system Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin‑induced diabetic mice.Notch: architect, landscaper, and guardian of the intestine.Streptozotocin-induced diabetes models: pathophysiological mechanisms and fetal outcomes Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells.Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival.Transdifferentiation: a cell and molecular reprogramming process.Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice Intestinal development and differentiation.The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice Complex regulation controls Neurogenin3 proteolysis.Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts.Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis.Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease.A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons.FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine A mouse model for monitoring islet cell genesis and developing therapies for diabetes

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P2860

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.

http://www.wikidata.org/entity/Q34361184

description

2002 nî lūn-bûn

@nan

2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

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2002年論文

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2002年论文

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name

Neurogenin3 is differentially ...... stinal and gastric epithelium.

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Neurogenin3 is differentially ...... stinal and gastric epithelium.

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Neurogenin3 is differentially ...... stinal and gastric epithelium.

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type

label

Neurogenin3 is differentially ...... stinal and gastric epithelium.

@ast

Neurogenin3 is differentially ...... stinal and gastric epithelium.

@en

Neurogenin3 is differentially ...... stinal and gastric epithelium.

@nl

prefLabel

Neurogenin3 is differentially ...... stinal and gastric epithelium.

@ast

Neurogenin3 is differentially ...... stinal and gastric epithelium.

@en

Neurogenin3 is differentially ...... stinal and gastric epithelium.

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The EMBO Journal

P1476

Neurogenin3 is differentially ...... stinal and gastric epithelium.

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Céline Uhl

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Francois Guillemot

http://www.w3.org/2001/XMLSchema#string

Marjorie Jenny

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Michèle Kedinger

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Valérie Guillermin

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P2860

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity

Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD

Notch signalling controls pancreatic cell differentiation

The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

Control of endodermal endocrine development by Hes-1

Math1: an essential gene for the generation of inner ear hair cells

Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

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6338-6347

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scholarly article

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10.1093/EMBOJ/CDF649

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P433

23

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21

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Gérard Gradwohl

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2002-12-01T00:00:00Z

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232787931

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12456641

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136953

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