Support for the multigenic hypothesis of amyloidosis: the binding stoichiometry of retinol-binding protein, vitamin A, and thyroid hormone influences transthyretin amyloidogenicity in vitro.
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New Class of Inhibitors of Amyloid-beta Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASETissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue cultureMechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin AmyloidosisA Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and CytotoxicityNovel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITIONTransthyretin variants with improved inhibition of β-amyloid aggregation.Progress in transthyretin fibrillogenesis research strengthens the amyloid hypothesis.The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.Recent progress in the understanding and treatment of transthyretin amyloidosis.Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity.Therapeutic strategies for human amyloid diseases.Evidence for defective retinoid transport and function in late onset Alzheimer's diseaseMechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs.Identification of beta-amyloid-binding sites on transthyretin.Transthyretin: the servant of many masters.The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.Current and future treatment of amyloid diseases.Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System.Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes.Formation of cytotoxic transthyretin is not dependent on inter-molecular disulphide bridges commonly found within the amyloid form.Inconsistency between hepatic expression and serum concentration of transthyretin in mice humanized at the transthyretin locus.The effects of vitamin A, pentoxyfylline and methylprednisolone on experimentally induced amyloid arthropathy in brown layer chicks.Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.Serum amyloid A in geese; cloning and expression of recombinant protein.Proteomic analysis of prognostic plasma biomarkers in peripheral arterial occlusive disease.Diabetes and overweight associate with non-APOE4 genotype in an Alzheimer's disease population.Stimulated interaction between and subunits of tryptophan synthase from hyperthermophile enhances its thermal stability.Understanding and Ameliorating the TTR AmyloidosesR104H may suppress transthyretin amyloidogenesis by thermodynamic stabilization, but not by the kinetic mechanism characterizing T119 interallelic trans-suppressionSpectroscopic Investigations of Pentobarbital Interaction with Transthyretin
P2860
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P2860
Support for the multigenic hypothesis of amyloidosis: the binding stoichiometry of retinol-binding protein, vitamin A, and thyroid hormone influences transthyretin amyloidogenicity in vitro.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@ast
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@en
type
label
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@ast
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@en
prefLabel
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@ast
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@en
P2860
P356
P1476
Support for the multigenic hyp ...... tin amyloidogenicity in vitro.
@en
P2093
P2860
P304
13019-13024
P356
10.1073/PNAS.241406698
P407
P577
2001-10-30T00:00:00Z