Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection. - Wikidata - awgldk - TriplyDB

Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection.

Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection.

http://www.wikidata.org/entity/Q33949267

about

Purinergic signaling in schistosomal infection IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis.IL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis.Dynamics of Th17 cells and their role in Schistosoma japonicum infection in C57BL/6 mice.Gene profile of chemokines on hepatic stellate cells of schistosome-infected mice and antifibrotic roles of CXCL9/10 on liver non-parenchymal cells Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis.An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum.Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis.TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis.Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study.The immunobiology of Th1 polarization in high-pathology schistosomiasis.Opposing roles for IL-13 and IL-13 receptor alpha 2 in health and disease.IFN-γ-driven IDO production from macrophages protects IL-4Rα-deficient mice against lethality during Schistosoma mansoni infection.Minor genomic differences between related B6 and B10 mice affect severity of schistosome infection by governing the mode of dendritic cell activation.Immunopathology of schistosomiasis Protective immune mechanisms in helminth infection IL-4 and IFN-γ induced by human immunodeficiency virus vaccine in a schistosome infection model.The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1β The schistosome in the mammalian host: understanding the mechanisms of adaptation.Induction and regulation of pathogenic Th17 cell responses in schistosomiasis.Coinfection with the intestinal nematode Heligmosomoides polygyrus markedly reduces hepatic egg-induced immunopathology and proinflammatory cytokines in mouse models of severe schistosomiasis.Myrrh and artesunate modulate some Th1 and Th2 cytokines secretion in Schistosoma mansoni infected mice Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology.Role of IL-17 and Th17 cells in liver diseases B10 cells induced by Schistosoma japonicum soluble egg antigens modulated regulatory T cells and cytokine production of T cells.Dendritic cell expression of the C-type lectin receptor CD209a: A novel innate parasite-sensing mechanism inducing Th17 cells that drive severe immunopathology in murine schistosome infection.Exacerbated egg-induced immunopathology in murine Schistosoma mansoni infection is primarily mediated by IL-17 and restrained by IFN-γ.Disruption of interleukin-27 signaling results in impaired gamma interferon production but does not significantly affect immunopathology in murine schistosome infection T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation.Naïve donor responses to Schistosoma mansoni soluble egg antigens.IL-17 neutralization significantly ameliorates hepatic granulomatous inflammation and liver damage in Schistosoma japonicum infected mice.Sex hormones alter Th1 responses and enhance granuloma formation in the lung.Dynamics of structural transformations of BCG granulomas and expression of TNF-α and granulocyte-macrophage CSF by macrophages in vitro.

P2860

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P2860

Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection.

http://www.wikidata.org/entity/Q33949267

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Th1-polarizing immunization wi ...... eath in schistosome infection.

@en

P2093

Hernandez HJ

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Rutitzky LI

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Stadecker MJ

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P2860

Schistosoma mansoni: genetic restriction and cytokine profile of the CD4 + T helper cell response to dominant epitope peptide of major egg antigen Sm-p40.

Other functions, other genes: alternative activation of antigen-presenting cells.

Educating T cells: early events in the differentiation and commitment of cytokine-producing CD4+ and CD8+ T cells.

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response.

The regulatory role of the antigen-presenting cell in the development of hepatic immunopathology during infection with Schistosoma mansoni.

Signaling and transcription in T helper development.

Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii

Hepatic schistosomiasis.

Mice lacking the gamma interferon receptor have an impaired granulomatous reaction to Schistosoma mansoni infection

Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.

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13243-13248

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10.1073/PNAS.231258498

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23

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98

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11743364

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11606762

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P921

schistosomiasis

P932

60855

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