The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation
about
Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dotsModeling the epigenetic attractors landscape: toward a post-genomic mechanistic understanding of developmentA general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativityLoads bias genetic and signaling switches in synthetic and natural systemsCancer tumors as Metazoa 1.0: tapping genes of ancient ancestorsClassification of transient behaviours in a time-dependent toggle switch modelCell Sorting and Noise-Induced Cell Plasticity Coordinate to Sharpen Boundaries between Gene Expression DomainsSystematic search for recipes to generate induced pluripotent stem cellsSingle cell proteomics in biomedicine: High-dimensional data acquisition, visualization and analysis.Reshaping the epigenetic landscape during early flower development: induction of attractor transitions by relative differences in gene decay rates.Cell lineage determination in state space: a systems view brings flexibility to dogmatic canonical rules.Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer.Predicting pancreas cell fate decisions and reprogramming with a hierarchical multi-attractor model.Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae.A deterministic map of Waddington's epigenetic landscape for cell fate specification.Interplay between path and speed in decision making by high-dimensional stochastic gene regulatory networks.From understanding the development landscape of the canonical fate-switch pair to constructing a dynamic landscape for two-step neural differentiation.Quantifying cell fate decisions for differentiation and reprogramming of a human stem cell network: landscape and biological paths.Hybrid T-helper cells: stabilizing the moderate center in a polarized system.Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.Quantifying the Waddington landscape and biological paths for development and differentiation.Two-phase dynamics of p53 in the DNA damage response.Epigenetic landscapes explain partially reprogrammed cells and identify key reprogramming genes.Exploring the mechanisms of differentiation, dedifferentiation, reprogramming and transdifferentiationStochastic dynamics of interacting haematopoietic stem cell niche lineages.Reliable binary cell-fate decisions based on oscillations.Energy landscape reveals that the budding yeast cell cycle is a robust and adaptive multi-stage process.Stability and multiattractor dynamics of a toggle switch based on a two-stage model of stochastic gene expression.Bistability, bifurcations, and Waddington's epigenetic landscape.Dynamical systems approach to endothelial heterogeneity.A new mechanism of stem cell differentiation through slow binding/unbinding of regulators to genesCell Fate Decision as High-Dimensional Critical State Transition.A physical mechanism of cancer heterogeneityEddy current and coupled landscapes for nonadiabatic and nonequilibrium complex system dynamics.Quantifying Waddington landscapes and paths of non-adiabatic cell fate decisions for differentiation, reprogramming and transdifferentiation.Nonequilibrium landscape theory of neural networks.Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspectiveVisualizing the appearance and disappearance of the attractor of differentiation using Raman spectral imaging.Deconstructing stem cell population heterogeneity: single-cell analysis and modeling approaches.Mathematical approaches to modeling development and reprogramming.
P2860
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P2860
The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The potential landscape of gen ...... e in stem cell differentiation
@ast
The potential landscape of gen ...... e in stem cell differentiation
@en
type
label
The potential landscape of gen ...... e in stem cell differentiation
@ast
The potential landscape of gen ...... e in stem cell differentiation
@en
prefLabel
The potential landscape of gen ...... e in stem cell differentiation
@ast
The potential landscape of gen ...... e in stem cell differentiation
@en
P2093
P2860
P1433
P1476
The potential landscape of gen ...... e in stem cell differentiation
@en
P2093
P2860
P356
10.1016/J.BPJ.2010.03.058
P407
P577
2010-07-01T00:00:00Z