p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption.
about
Expression of cyclins A, E and topoisomerase II alpha correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determinationSenescence from G2 arrest, revisitedCell Cycle-Dependent Localization of Dynactin Subunit p150 glued at CentrosomeCyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest8-Cl-adenosine-induced inhibition of colorectal cancer growth in vitro and in vivoTumor suppressors and cell-cycle proteins in lung cancerNovel roles for p53 in the genesis and targeting of tetraploid cancer cellsGrowth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated proteinDifferent susceptibilities of postmitotic checkpoint-proficient and -deficient Balb / 3T3 cells to ICRF-193, a catalytic inhibitor of DNA topoisomerase II.Colorectal carcinogenesis: road maps to cancer.Kinetics of p53 binding to promoter sites in vivo.The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.CARP is a potential tumor suppressor in gastric carcinoma and a single-nucleotide polymorphism in CARP gene might increase the risk of gastric carcinoma.Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.Significance of multiple mutations in cancer.Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.DNA replication and smooth muscle cell hypertrophy.ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy.Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.Strategies for manipulating the p53 pathway in the treatment of human cancer.AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival.Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery.Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.Blocking effects of genistein on cell proliferation and possible mechanism in human gastric carcinomaGenomic Instability Induced By Human Papillomavirus Oncogenes.Cardiac progenitor cell cycling stimulated by pim-1 kinaseRole of Cdk1 in the p53-independent abrogation of the postmitotic checkpoint by human papillomavirus E6Synergistic antimicrotubule therapy for prostate cancerAging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expressionp53: guardian of ploidyThe in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cellsSelect host restriction factors are associated with HIV persistence during antiretroviral therapy.Aurora-A - a guardian of poles.Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation.Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins.MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice.MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progressionBasal keratinocyte tetrasomy in low-grade squamous intra-epithelial lesions of the cervix is restricted to high and intermediate risk HPV infection but is not type-specificP21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
P2860
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P2860
p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@ast
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@en
type
label
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@ast
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@en
prefLabel
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@ast
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@en
P2093
P2860
P356
P1476
p21(Waf1/Cip1) inhibition of c ...... er mitotic spindle disruption.
@en
P2093
J A Pietenpol
Z A Stewart
P2860
P304
P356
10.1128/MCB.19.1.205
P407
P577
1999-01-01T00:00:00Z