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Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation ExposureConnecting Malfunctioning Glial Cells and Brain Degenerative DisordersGenome Engineering with TALE and CRISPR Systems in NeuroscienceThe Response to Oxidative DNA Damage in Neurons: Mechanisms and DiseasePrion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage responseConnecting the dots between tau dysfunction and neurodegenerationSystemic DNA damage responses in aging and diseasesPot1a prevents telomere dysfunction and ATM-dependent neuronal loss.Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromesParkin regulates translesion DNA synthesis in response to UV radiationSmall organelle, big responsibility: the role of centrosomes in development and disease.Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response GenesHigh-resolution copy number variation analysis of schizophrenia in Japan.The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterizationIncreased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina.Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.DNA damage and its links to neurodegeneration.DNA repair abnormalities leading to ataxia: shared neurological phenotypes and risk factors.Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain developmentRan Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells.The DNA damage response molecule MCPH1 in brain development and beyond.Evasion of cell senescence in SHH medulloblastoma.Topoisomerases and the regulation of neural function.In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory.A Critical Balance: dNTPs and the Maintenance of Genome StabilityProtein Phosphorylation is a Key Mechanism in Alzheimer's Disease.Neurodegeneration in ataxia-telangiectasia: Multiple roles of ATM kinase in cellular homeostasis.Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.A MYCN-MRN complex axis controls replication stress for the safe expansion of neuroprogenitor cells.Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic diseaseCdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.Lamin Dysfunction Mediates Neurodegeneration in Tauopathies.Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Maintaining genome stability in the nervous system.
@ast
Maintaining genome stability in the nervous system.
@en
type
label
Maintaining genome stability in the nervous system.
@ast
Maintaining genome stability in the nervous system.
@en
prefLabel
Maintaining genome stability in the nervous system.
@ast
Maintaining genome stability in the nervous system.
@en
P2860
P356
P1433
P1476
Maintaining genome stability in the nervous system.
@en
P2093
Peter J McKinnon
P2860
P2888
P304
P356
10.1038/NN.3537
P407
P577
2013-10-28T00:00:00Z