Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
about
ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53DNA polymerase θ (POLQ), double-strand break repair, and cancerTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseNeurogenomics and the role of a large mutational target on rapid behavioral changeBridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry.High-resolution copy number variation analysis of schizophrenia in Japan.Rescue from replication stress during mitosis.Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencingA Signature of Genomic Instability Resulting from Deficient Replication Licensing.Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.Highly sensitive and unbiased approach for elucidating antibody repertoires.When Genome Maintenance Goes Badly Awry.PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress.TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcriptionGenome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.Mosaicism in health and disease - clones picking up speed.Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond.Conflict Resolution in the Genome: How Transcription and Replication Make It Work.In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory.DNA repair and mutations during quiescence in yeast.Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.Physiological functions of programmed DNA breaks in signal-induced transcription.Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.Fragile sites in cancer: more than meets the eye.Environmental change drives accelerated adaptation through stimulated copy number variation.Examining non-LTR retrotransposons in the context of the evolving primate brain.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cells.Shining a light on early stress responses and late-onset disease vulnerability.Retrotransposing Gremlins May Disrupt Our Brain's Genomes.A Upf3b-mutant mouse model with behavioral and neurogenesis defects.The cat in between: Nature, nurture, . . . neither!Replication stress induces accumulation of FANCD2 at central region of large fragile genes.FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells.Genetic insights into the neurodevelopmental origins of schizophrenia.Failure to Inactivate Nuclear GSK3β by Ser389-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response.Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders.Activity-DEPendent Transposition.Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination.
P2860
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P2860
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@ast
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@en
type
label
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@ast
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@en
prefLabel
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@ast
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
@en
P2093
P2860
P1433
P1476
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells
@en
P2093
Amelia N Chang
Bjoern Schwer
Frederick W Alt
Jennifer Kao
P2860
P304
P356
10.1016/J.CELL.2015.12.039
P407
P577
2016-02-01T00:00:00Z