Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster.
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Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functionsThe winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcriptionHairy transcriptional repression targets and cofactor recruitment in DrosophilaThe Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee.NF-kappaB/Rel-mediated regulation of the neural fate in DrosophilaThe WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domainA conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos.Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.The nuclear protein encoded by the Drosophila neurogenic gene mastermind is widely expressed and associates with specific chromosomal regions.Analysis of dominant enhancers and suppressors of activated Notch in Drosophila.Genetic interactions between naturally occurring alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila melanogaster.The Enhancer of split complex arose prior to the diversification of schizophoran flies and is strongly conserved between Drosophila and stalk-eyed flies (Diopsidae)Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression.A novel interaction between hedgehog and Notch promotes proliferation at the anterior-posterior organizer of the Drosophila wing.Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning.eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins.Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed.In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters.Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling.The Conserved MAPK Site in E(spl)-M8, an Effector of Drosophila Notch Signaling, Controls Repressor Activity during Eye DevelopmentDrosophila evolution challenges postulated redundancy in the E(spl) gene complex.A chimeric enhancer-of-split transcriptional activator drives neural development and achaete-scute expression.Groucho-dependent and -independent repression activities of Runt domain proteinsA network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system.The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor.On the mechanism underlying the divergent retinal and bristle defects of M8* (E(spl)D) in Drosophila.Position dependent responses to discontinuities in the retinal determination network.Phosphorylated Groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of EGFR signaling in the niche.Target specificities of Drosophila enhancer of split basic helix-loop-helix proteins.The Groucho/TLE/Grg family of transcriptional co-repressors.bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stabilityEssential roles of Da transactivation domains in neurogenesis and in E(spl)-mediated repression.Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors.
P2860
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P2860
Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster.
description
1991 nî lūn-bûn
@nan
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Two genetically and molecularl ...... us of Drosophila melanogaster.
@ast
Two genetically and molecularl ...... us of Drosophila melanogaster.
@en
type
label
Two genetically and molecularl ...... us of Drosophila melanogaster.
@ast
Two genetically and molecularl ...... us of Drosophila melanogaster.
@en
prefLabel
Two genetically and molecularl ...... us of Drosophila melanogaster.
@ast
Two genetically and molecularl ...... us of Drosophila melanogaster.
@en
P2093
P2860
P1433
P1476
Two genetically and molecularl ...... us of Drosophila melanogaster.
@en
P2093
C Delidakis
D A Hartley
S Artavanis-Tsakonas
P2860
P304
P407
P577
1991-11-01T00:00:00Z