Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation
about
Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell responseAddressing current challenges in cancer immunotherapy with mathematical and computational modelling.Redirecting T cells to Ewing's sarcoma family of tumors by a chimeric NKG2D receptor expressed by lentiviral transduction or mRNA transfection.NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine.Challenges and opportunities of allogeneic donor-derived CAR T cellsA fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity.Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.Highlights of the second international conference on "Immunotherapy in Pediatric Oncology".Chimeric antigen receptor modified T cell therapy for B cell malignancies.Adoptive immunotherapy for cancer or viruses.Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase.Treatment of advanced leukemia in mice with mRNA engineered T cells.A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs).Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer.Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia.
P2860
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P2860
Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mathematical modeling of chime ...... pairment by TCR downmodulation
@ast
Mathematical modeling of chime ...... pairment by TCR downmodulation
@en
type
label
Mathematical modeling of chime ...... pairment by TCR downmodulation
@ast
Mathematical modeling of chime ...... pairment by TCR downmodulation
@en
prefLabel
Mathematical modeling of chime ...... pairment by TCR downmodulation
@ast
Mathematical modeling of chime ...... pairment by TCR downmodulation
@en
P2093
P2860
P356
P1476
Mathematical modeling of chime ...... pairment by TCR downmodulation
@en
P2093
Andrew A Raubitschek
Brian G Till
Jinjuan Wang
Lihua E Budde
Michael C Jensen
Philip D Greenberg
Scott E James
Stephen J Forman
Yukang Lin
P2860
P304
P356
10.4049/JIMMUNOL.0903701
P407
P577
2010-03-10T00:00:00Z