Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.
about
Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)Murine and human CFTR exhibit different sensitivities to CFTR potentiators.Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulatorSpatial positioning of CFTR's pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathwayAltering intracellular pH reveals the kinetic basis of intraburst gating in the CFTR Cl- channel.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.Electrostatic tuning of the pre- and post-hydrolytic open states in CFTRArchitecture and functional properties of the CFTR channel pore.On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator.The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor.Potentiators exert distinct effects on human, murine, and Xenopus CFTR.External Zn(2+) binding to cysteine-substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation.Structural mechanisms of CFTR function and dysfunction.
P2860
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P2860
Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Three charged amino acids in e ...... ter pore architecture of CFTR.
@ast
Three charged amino acids in e ...... ter pore architecture of CFTR.
@en
type
label
Three charged amino acids in e ...... ter pore architecture of CFTR.
@ast
Three charged amino acids in e ...... ter pore architecture of CFTR.
@en
prefLabel
Three charged amino acids in e ...... ter pore architecture of CFTR.
@ast
Three charged amino acids in e ...... ter pore architecture of CFTR.
@en
P2093
P2860
P356
P1476
Three charged amino acids in e ...... ter pore architecture of CFTR.
@en
P2093
Chengyu Z Prince
Christopher Kuang
Daniel T Infield
Guiying Cui
Kazi S Rahman
Nael A McCarty
P2860
P304
P356
10.1085/JGP.201311122
P577
2014-07-14T00:00:00Z