Identification of a methylation imprint mark within the mouse Gnas locus.
about
Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolutionMethylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnanciesA novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNASDiagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS-based heterotopic ossificationGlobal transcriptome analysis of the C57BL/6J mouse testis by SAGE: evidence for nonrandom gene order.The GNAS complex locus and human diseases associated with loss-of-function mutations or epimutations within this imprinted geneGene Dosage Effects at the Imprinted Gnas ClusterGNAS locus and pseudohypoparathyroidismImprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegalyIdentification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunitMaternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growthTargeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-IbThe evolution of mammalian genomic imprinting was accompanied by the acquisition of novel CpG islandsSelective resistance to parathyroid hormone caused by a novel uncoupling mutation in the carboxyl terminus of G alpha(s). A cause of pseudohypoparathyroidism type Ib.The importance of imprinting in the human placenta.A comprehensive transcript map of the mouse Gnas imprinted complex.Imprinted Nesp55 influences behavioral reactivity to novel environmentsThe function of non-coding RNAs in genomic imprinting.Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island.Discordance between genetic and epigenetic defects in pseudohypoparathyroidism type 1b revealed by inconsistent loss of maternal imprinting at GNAS1Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome.Retrotransposition and genomic imprinting.Deletion of the noncoding GNAS antisense transcript causes pseudohypoparathyroidism type Ib and biparental defects of GNAS methylation in cisThe role of GNAS and other imprinted genes in the development of obesity.Imprints of disease at GNAS1.A GNAS1 imprinting defect in pseudohypoparathyroidism type IBPotent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune-Albright syndrome and fibrous dysplasia of bone.Pseudohypoparathyroidism: one gene, several syndromes.Effects of deficiency of the G protein Gsα on energy and glucose homeostasisOntogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse.The silence RNA keeps: cis mechanisms of RNA mediated epigenetic silencing in mammals.Epigenetic properties and identification of an imprint mark in the Nesp-Gnasxl domain of the mouse Gnas imprinted locus.Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies.Imprinting status of Galpha(s), NESP55, and XLalphas in cell cultures derived from human embryonic germ cells: GNAS imprinting in human embryonic germ cellsBio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNANew mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling.Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.
P2860
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P2860
Identification of a methylation imprint mark within the mouse Gnas locus.
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Identification of a methylation imprint mark within the mouse Gnas locus.
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Identification of a methylation imprint mark within the mouse Gnas locus.
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label
Identification of a methylation imprint mark within the mouse Gnas locus.
@ast
Identification of a methylation imprint mark within the mouse Gnas locus.
@en
prefLabel
Identification of a methylation imprint mark within the mouse Gnas locus.
@ast
Identification of a methylation imprint mark within the mouse Gnas locus.
@en
P2093
P2860
P1476
Identification of a methylation imprint mark within the mouse Gnas locus.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.16.5808-5817.2000
P407
P577
2000-08-01T00:00:00Z