The role of GNAS and other imprinted genes in the development of obesity.
about
What obesity research tells us about epigenetic mechanismsEpidemiology and Diagnosis of Hypoparathyroidism.DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traitsOsteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots.Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations.Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/JxSM/J murine modelPostnatal changes in the expression pattern of the imprinted signalling protein XLαs underlie the changing phenotype of deficient mice.Genomic imprinting in diabetes.The role of genomic imprinting in biology and disease: an expanding view.Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes.Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults.New mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling.A Homozygous [Cys25]PTH(1-84) Mutation That Impairs PTH/PTHrP Receptor Activation Defines a Novel Form of Hypoparathyroidism.Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo.mRNA Levels of Imprinted Genes in Bovine In Vivo Oocytes, Embryos and Cross Species Comparisons with Humans, Mice and Pigs.G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortinsGsα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight.Analysis of Multiple Families With Single Individuals Affected by Pseudohypoparathyroidism Type Ib (PHP1B) Reveals Only One Novel Maternally Inherited GNAS DeletionThe importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J × SM/J murine model.Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort.Epigenomics, gestational programming and risk of metabolic syndrome.Different roles of GNAS and cAMP signaling during early and late stages of osteogenic differentiation.Analysis of the associations between polymorphisms in GNAS complex locus and growth, carcass and meat quality traits in pigs.Parental programming: how can we improve study design to discern the molecular mechanisms?A novel deletion involving GNAS exon 1 causes PHP1A and further refines the region required for normal methylation at exon A/B.A Large Inversion Involving GNAS Exon A/B and All Exons Encoding Gsα Is Associated With Autosomal Dominant Pseudohypoparathyroidism Type Ib (PHP1B).Classic and Non-Classic Features in Pseudohypoparathyroidism: Case Study and Brief Literature Review.DNA methylation variability at growth-related imprints does not contribute to overweight in monozygotic twins discordant for BMI.Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans
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The role of GNAS and other imprinted genes in the development of obesity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The role of GNAS and other imprinted genes in the development of obesity.
@ast
The role of GNAS and other imprinted genes in the development of obesity.
@en
The role of GNAS and other imprinted genes in the development of obesity.
@nl
type
label
The role of GNAS and other imprinted genes in the development of obesity.
@ast
The role of GNAS and other imprinted genes in the development of obesity.
@en
The role of GNAS and other imprinted genes in the development of obesity.
@nl
prefLabel
The role of GNAS and other imprinted genes in the development of obesity.
@ast
The role of GNAS and other imprinted genes in the development of obesity.
@en
The role of GNAS and other imprinted genes in the development of obesity.
@nl
P2093
P2860
P356
P1476
The role of GNAS and other imprinted genes in the development of obesity
@en
P2093
P2860
P2888
P356
10.1038/IJO.2009.222
P407
P577
2009-10-20T00:00:00Z
P5875
P6179
1046839271