Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. - Wikidata - awgldk - TriplyDB

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.

http://www.wikidata.org/entity/Q33965313

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The Janus kinases (Jaks)The tyrosine kinase Syk regulates TPL2 activation signals TYK2 is a key regulator of the surveillance of B lymphoid tumors A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity Immunomodulatory functions of type I interferons Tyrosine phosphorylation in Toll-like receptor signaling The regulation of inflammation by interferons and their STATs A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses Regulation of the type I IFN induction: a current view Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 Type I interferon: friend or foe?A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1 TYK2 kinase activity is required for functional type I interferon responses in vivo Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages.Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators A time- and dose-dependent STAT1 expression system.Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses.Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27 FAS-associated factor-1 positively regulates type I interferon response to RNA virus infection by targeting NLRX1.TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming The role of CXCL10 in the pathogenesis of experimental septic shock Production of IFN-β during Listeria monocytogenes infection is restricted to monocyte/macrophage lineage Mucosal immunotherapy for protection from pneumonic infection with Francisella tularensis Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria The molecular regulation of Janus kinase (JAK) activation Differential induction of innate immune responses by synthetic lipid a derivatives Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenes.Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT Interferon-alpha administration enhances CD8+ T cell activation in HIV infection An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages.Endotoxin recognition: in fish or not in fish?The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production.Yohimbine enhances protection of berberine against LPS-induced mouse lethality through multiple mechanisms.Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression.Activation of common antiviral pathways can potentiate inflammatory responses to septic shock.Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses.

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P2860

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.

http://www.wikidata.org/entity/Q33965313

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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Central role for type I interf ...... aride-induced endotoxin shock.

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Central role for type I interf ...... aride-induced endotoxin shock.

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Central role for type I interf ...... aride-induced endotoxin shock.

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Central role for type I interf ...... aride-induced endotoxin shock.

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Nature Immunology

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Central role for type I interf ...... aride-induced endotoxin shock.

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Birgit Donabauer

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Gernot Kriegshäuser

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Marina Karaghiosoff

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Ralf Steinborn

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Thomas Decker

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10.1038/NI910

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5

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4

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Manuela Baccarini

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