Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts
about
Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblastsCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsCompetition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.ZKSCAN3 is a master transcriptional repressor of autophagyControl of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1p35 is required for CDK5 activation in cellular senescence.Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence.Regulation of cellular senescence by p53.The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation.Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion.Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21Geroconversion: irreversible step to cellular senescenceInverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.Low-dose etoposide-treatment induces endoreplication and cell death accompanied by cytoskeletal alterations in A549 cells: Does the response involve senescence? The possible role of vimentin.Telomere dynamics: the means to an end.Identification of cellular senescence-specific genes by comparative transcriptomics.Redox control of the cell cycle in health and disease.Deconstructing p53 transcriptional networks in tumor suppression.Molecular pathology endpoints useful for aging studies.Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cellsPermanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts.Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts.Cellular senescence requires CDK5 repression of Rac1 activity.Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome.Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1).A codon 31ser-arg polymorphism of the WAF-1/CIP-1/p21/tumour suppressor gene in Chinese primary open-angle glaucoma.A role for p53 in maintaining and establishing the quiescence growth arrest in human cells.Early loss of proliferative potential of human peritoneal mesothelial cells in culture: the role of p16INK4a-mediated premature senescence.
P2860
Q24294537-955D4864-F3EA-450D-93EE-E9817F25E366Q24302257-35C627C6-8674-4F75-984F-8B0E78C32755Q24305100-350DEC23-AA65-484D-A08A-A5F4C4A34C68Q24319594-47F27B69-4C63-4B8B-AB95-8A0DEF294123Q24540711-333FFB45-EAAF-4AC0-B619-078B4CBA786EQ33825111-D9D11971-C4D9-42C4-8FBE-D7A2BB4FE2DFQ33968178-FCF952E5-7D83-4B88-B648-330736FB9E79Q34254621-0755EEA5-F8C8-4C00-BC2C-297817400AD4Q34352305-F310CB51-AAD0-4F0B-B307-F16F7CBBF709Q35072584-0F50147D-7E62-4099-939F-CB300F8AD81EQ35149607-B6D16E64-65E2-4550-A3C5-5E7785DC82BFQ35879963-65375183-5F15-4107-B14E-1E5A329CC92EQ36186369-A1DC09BB-66E8-4137-9794-EECBFD245D40Q36201349-CEAFB5FA-D5E6-4471-B615-221F514FAB60Q36357596-3F8FDA80-1E6D-48C3-92EC-603328BFA5EBQ36689527-6170AC44-0BB6-45C6-9156-AAE709FE56C1Q36884191-D9D09241-0960-4F87-9709-9126EB1DA026Q37193100-73C74D22-8F7C-4381-B228-1095439A6D12Q37510851-DA9ED8FA-48B0-45C9-B6A8-176B86B557C7Q37966330-9A6BED93-8C3C-4673-AF5F-C8F40DCFC282Q38435673-32DC3D5F-D767-4C61-B4CB-4762D78C60DAQ39804680-3B162014-B95B-4C43-939E-B0B2DBD874CDQ39804772-1062FEAB-FC59-4C5C-8730-B3868034DAEEQ40451759-6A7DCB19-2C87-4FA7-9F0D-764A21A70973Q40578044-4403392C-530A-4572-93D9-3F259735CB19Q42630985-EDABA402-782B-47DE-9C60-0ED70C3F27FEQ42643410-34F2F88D-E4EB-48F7-9210-8C9990A6310CQ43745848-51AD7A4D-0D15-4CC3-8FAA-3176527D3068Q44738392-8620B60C-617F-4A2D-B70A-9245EC58EA86Q46253755-68B5F476-1BC3-4E36-9AFB-18D24FF8521EQ54633769-D38DF6D9-ED3E-42F7-8AF9-98F52EC2D949
P2860
Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@ast
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@en
type
label
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@ast
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@en
prefLabel
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@ast
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@en
P2093
P2860
P1476
Uncoupling between phenotypic ...... ging p21-deficient fibroblasts
@en
P2093
G Frebourg
L F Drullinger
P2860
P304
P356
10.1128/MCB.20.18.6741-6754.2000
P407
P577
2000-09-01T00:00:00Z