Donor CD8 T cell activation is critical for greater renal disease severity in female chronic graft-vs.-host mice and is associated with increased splenic ICOS(hi) host CD4 T cells and IL-21 expression
about
Advances in lupus stemming from the parent-into-F1 modelIL2-IL21 gene cluster polymorphism is not associated with allograft function after kidney transplantation.Pre-clinical screening of immunomodulatory compounds using the parent-into-F1 model.Donor CD8 T cells and IFN-gamma are critical for sex-based differences in donor CD4 T cell engraftment and lupus-like phenotype in short-term chronic graft-versus-host disease mice.Intrinsic Differences in Donor CD4 T Cell IL-2 Production Influence Severity of Parent-into-F1 Murine Lupus by Skewing the Immune Response Either toward Help for B Cells and a Sustained Autoantibody Response or toward Help for CD8 T Cells and a DownIL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.T cells, murine chronic graft-versus-host disease and autoimmunity.In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-versus-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor.
P2860
Q33903169-0538A195-44D1-4183-A6AB-7F17FF323BA2Q34587940-52C6012C-933B-4F34-8109-A684BE7FFADCQ35547577-3F04BCC5-835B-4FA8-9CC3-0D2E4DB8F682Q35547605-805DB886-F540-4978-A867-F1514016883BQ36075382-E56EC458-9D57-46DB-A2EF-7A174354D6CFQ36084270-9C1EF722-1661-4A7A-AF40-3C660E18B9F9Q36626989-671D7FFC-8878-4B49-984D-559EF4CE1D26Q36788495-E7A97BB4-5526-42FF-A568-BFA66020E0C3
P2860
Donor CD8 T cell activation is critical for greater renal disease severity in female chronic graft-vs.-host mice and is associated with increased splenic ICOS(hi) host CD4 T cells and IL-21 expression
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@ast
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@en
type
label
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@ast
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@en
prefLabel
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@ast
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@en
P2093
P2860
P1433
P1476
Donor CD8 T cell activation is ...... 4 T cells and IL-21 expression
@en
P2093
Anthony D Foster
Charles S Via
Irina Puliaeva
Kateryna Soloviova
Roman Puliaev
P2860
P356
10.1016/J.CLIM.2010.01.005
P577
2010-05-06T00:00:00Z