Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.
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Xenobiotic acceleration of idiopathic systemic autoimmunity in lupus-prone bxsb miceLupus-prone mice as models to study xenobiotic-induced acceleration of systemic autoimmunityBreaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis.Autoantibodies in lupus nephritis patients requiring renal transplantation.Defective B-cell response to T-dependent immunization in lupus-prone miceGenetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies.Donor CD8 T cell activation is critical for greater renal disease severity in female chronic graft-vs.-host mice and is associated with increased splenic ICOS(hi) host CD4 T cells and IL-21 expressionEpstein-Barr virus and molecular mimicry in systemic lupus erythematosus.Genetics of systemic autoimmunity in mouse models of lupus.Lessons from the NZM2410 model and related strains.Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus.Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo.The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus.The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosusTriggers for anti-chromatin autoantibody production in SLE.Implications of the parent-into-F1 model for human lupus pathogenesis: roles for cytotoxic T lymphocytes and viral pathogens.Anti-chromatin antibodies in systemic lupus erythematosus: a useful marker for lupus nephropathy.Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host diseaseDivergent members of a single autoreactive B cell clone retain specificity for apoptotic blebsEstrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice.Altered autoantigen structure in Sjögren's syndrome: implications for the pathogenesis of autoimmune tissue damage.Lupus susceptibility loci in New Zealand mice.Intrinsic Differences in Donor CD4 T Cell IL-2 Production Influence Severity of Parent-into-F1 Murine Lupus by Skewing the Immune Response Either toward Help for B Cells and a Sustained Autoantibody Response or toward Help for CD8 T Cells and a DownStructure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA.Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupusType-I interferon receptor deficiency reduces lupus-like disease in NZB mice.Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern.Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus miceIgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE.Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.Heterogeneity and clinical significance of glomerular-binding antibodies in systemic lupus erythematosus.Autoimmunity caused by disruption of central T cell tolerance. A murine model of drug-induced lupus.Roles of interferon-gamma and interleukin-4 in murine lupus.Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice.Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes.Role of peroxynitrite-modified biomolecules in the etiopathogenesis of systemic lupus erythematosus.The spectrum of anti-chromatin/nucleosome autoantibodies: independent and interdependent biomarkers of disease.Cell lines that express membrane-associated DNA for anti-DNA antibody detection.
P2860
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P2860
Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Genesis and evolution of antic ...... mmunization with self antigen.
@ast
Genesis and evolution of antic ...... mmunization with self antigen.
@en
type
label
Genesis and evolution of antic ...... mmunization with self antigen.
@ast
Genesis and evolution of antic ...... mmunization with self antigen.
@en
prefLabel
Genesis and evolution of antic ...... mmunization with self antigen.
@ast
Genesis and evolution of antic ...... mmunization with self antigen.
@en
P2093
P2860
P356
P1476
Genesis and evolution of antic ...... mmunization with self antigen.
@en
P2093
A N Theofilopoulos
R S Balderas
R W Burlingame
P2860
P304
P356
10.1172/JCI116378
P407
P577
1993-04-01T00:00:00Z