Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.
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Novel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic)Advances in graft-versus-host disease biology and therapy.Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells.The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells.The role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host diseaseImpaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection.Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution.Mechanisms of antigen presentation to T cells in murine graft-versus-host disease: cross-presentation and the appearance of cross-presentation.Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunityHY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host DiseaseCholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophage: anti-inflammatory effect of cholecystokinin.Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation.Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation?Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells.Regulatory T cells and IL-17-producing cells in graft-versus-host disease.GVHD prevention: an ounce is better than a pound.The role of dendritic cells in graft-versus-tumor effectImmunomodulatory Drugs: Immune Checkpoint Agents in Acute Leukemia.Minor histocompatibility Ags: identification strategies, clinical results and translational perspectives.Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy.PD-1 blockade for relapsed lymphoma post-allogeneic hematopoietic cell transplant: high response rate but frequent GVHD.PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells.Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning.Immunotherapy of Lymphoma and Myeloma: Facts and Hopes.Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen.Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers.Clinical Development of PD-1 Blockade in Hematologic Malignancies.Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice.Peripheral tissues reprogram CD8+ T cells for pathogenicity during graft-versus-host disease.
P2860
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P2860
Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@ast
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@en
type
label
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@ast
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@en
prefLabel
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@ast
Alloantigen expression on non- ...... rsus-leukemia effects in mice.
@en
P2093
P2860
P356
P1476
Alloantigen expression on non- ...... ersus-leukemia effects in mice
@en
P2093
Haruko Sugiyama
Koichi Akashi
Mitsune Tanimoto
Shoji Asakura
Shuichiro Takashima
Yoshinobu Maeda
P2860
P304
P356
10.1172/JCI39165
P407
P577
2010-06-07T00:00:00Z