The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals
about
Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathioneActivation of gene expression by metal-responsive signal transduction pathways.A novel cysteine cluster in human metal-responsive transcription factor 1 is required for heavy metal-induced transcriptional activation in vivoRegulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcriptionMetal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparisonInhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in developmentEnhanced oxidative stress resistance through activation of a zinc deficiency transcription factor in Brachypodium distachyonA CCCH zinc finger conserved in a replication protein a homolog found in diverse EuryarchaeotesTetrahymena metallothioneins fall into two discrete subfamilies.Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila.Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes.Differential Induction of Proteins in Anopheles gambiae sensu stricto (Diptera: Cullicidae) Larvae in Response to Heavy Metal SelectionThe parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1)A regulator of nutritional copper signaling in Chlamydomonas is an SBP domain protein that recognizes the GTAC core of copper response element.Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis.A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zincThe role of small ubiquitin-like modifier-interacting motif in the assembly and regulation of metal-responsive transcription factor 1.Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance.Genetic screen for regulators of lymph gland homeostasis and hemocyte maturation in Drosophila.Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain.Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.Functional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules.Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activationCopper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.Zinc deficiency impacts CO2 assimilation and disrupts copper homeostasis in Chlamydomonas reinhardtii.Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein.Expression of metallothionein and alpha-tubulin in heavy metal-tolerant Anopheles gambiae sensu stricto (Diptera: Culicidae).Metal-responsive transcription factor 1 (MTF-1) activity is regulated by a nonconventional nuclear localization signal and a metal-responsive transactivation domain.The Intestinal Copper Exporter CUA-1 Is Required for Systemic Copper Homeostasis in Caenorhabditis elegans.Natural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster.What can flies tell us about copper homeostasis?Identification and functional characterization of MRE-binding transcription factor (MTF) in Crassostrea gigas and its conserved role in metal-induced response.Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity.Mammalian metal response element-binding transcription factor-1 functions as a zinc sensor in yeast, but not as a sensor of cadmium or oxidative stress.Zinc induces caspase-dependent mitochondrial pathway of the programmed cell death in haemocytes of Drosophila melanogaster.Coactivator cross-talk specifies transcriptional output.The six zinc fingers of metal-responsive element binding transcription factor-1 form stable and quasi-ordered structures with relatively small differences in zinc affinities.Characterization of MtnE, the fifth metallothionein member in Drosophila.
P2860
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P2860
The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The Drosophila homolog of mamm ...... on in response to heavy metals
@ast
The Drosophila homolog of mamm ...... on in response to heavy metals
@en
type
label
The Drosophila homolog of mamm ...... on in response to heavy metals
@ast
The Drosophila homolog of mamm ...... on in response to heavy metals
@en
prefLabel
The Drosophila homolog of mamm ...... on in response to heavy metals
@ast
The Drosophila homolog of mamm ...... on in response to heavy metals
@en
P2093
P2860
P1476
The Drosophila homolog of mamm ...... on in response to heavy metals
@en
P2093
P2860
P304
P356
10.1128/MCB.21.14.4505-4514.2001
P407
P577
2001-07-01T00:00:00Z